A randomized, controlled double-blind study comparing the efficacy and safety of dose-ranging voclosporin with placebo in achieving remission in patients with active lupus nephritis - Rovin, Brad H.; Solomons, Neil; Pendergraft, William F.; Dooley, Mary Anne; Tumlin, James; Romero-Diaz, Juanita; Lysenko, Lidia; Navarra, Sandra V.; Huizinga, Robert B.; Adzerikho, Ihar; Mikhailova, Elena; Mitkovskaya, Natalya; et al. (Kidney international, 2019)
Keywords: Adult; calcineurin inhibitors; Calcineurin Inhibitors - administration & dosage; Calcineurin Inhibitors - adverse effects; Cyclosporine - administration & dosage; Cyclosporine - adverse effects; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination - adverse effects; Drug Therapy, Combination - methods; Female; glomerulonephritis; Glucocorticoids - administration & dosage; Glucocorticoids - adverse effects; Humans; Immunosuppressive Agents - administration & dosage; Immunosuppressive Agents - adverse effects; kidney biopsy; Lupus Nephritis - drug therapy; Lupus Nephritis - mortality; Male; Mycophenolic Acid - administration & dosage; Mycophenolic Acid - adverse effects; proteinuria; Remission Induction - methods; systemic lupus erythematosus; Treatment Outcome; Young Adult; systemic lupus erythematosus; kidney biopsy; glomerulonephritis; proteinuria; calcineurin inhibitors