Prevalence and clinical effect of caesarean scar defects in women undergoing IVF
How common are caesarean scar defects (isthmocele) among patients who have had previous caesarean delivery undergoing IVF for secondary infertility? Does the presence of isthmocele affect the chances of success of IVF? In this cohort study, women referred to an Italian public assisted reproduction c...
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| Published in | Reproductive biomedicine online Vol. 47; no. 4; p. 103240 |
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| Main Authors | , , , , , , , |
| Format | Journal Article |
| Language | English |
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Elsevier Ltd
01.10.2023
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| Abstract | How common are caesarean scar defects (isthmocele) among patients who have had previous caesarean delivery undergoing IVF for secondary infertility? Does the presence of isthmocele affect the chances of success of IVF?
In this cohort study, women referred to an Italian public assisted reproduction centre between January 2016 and April 2021 were retrospectively reviewed. Women with a history of caesarean delivery and an indication for IVF were selected. On the basis of the local policy, all patients with a history of caesarean section underwent saline contrast sonography (SCS). Sonographic evaluation was standardized.
One hundred and forty-four women were eligible, of whom 22 declined SCS and eight decided to delay pregnancy seeking. Overall, 114 women were available for data analysis. Seventy-six women were diagnosed with caesarean scar defects, corresponding to a prevalence of 67% (95% CI 58 to 75%). Baseline characteristics of women with and without isthmocele were similar. Conversely, the clinical pregnancy rate (adjusted OR 0.31, 95% CI 0.13 to 0.72) and live birth rate (adjusted OR 038, 95% CI 0.17 to 0.86) were significantly lower among affected women. No associations between specific sonographic defect characteristics and IVF outcome could be identified.
Caesarean scar defects are common among women with a history of caesarean section requiring IVF. The presence of these lesions may reduce the chance of success of the procedure. |
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| AbstractList | RESEARCH QUESTIONHow common are caesarean scar defects (isthmocele) among patients who have had previous caesarean delivery undergoing IVF for secondary infertility? Does the presence of isthmocele affect the chances of success of IVF? DESIGNIn this cohort study, women referred to an Italian public assisted reproduction centre between January 2016 and April 2021 were retrospectively reviewed. Women with a history of caesarean delivery and an indication for IVF were selected. On the basis of the local policy, all patients with a history of caesarean section underwent saline contrast sonography (SCS). Sonographic evaluation was standardized. RESULTSOne hundred and forty-four women were eligible, of whom 22 declined SCS and eight decided to delay pregnancy seeking. Overall, 114 women were available for data analysis. Seventy-six women were diagnosed with caesarean scar defects, corresponding to a prevalence of 67% (95% CI 58 to 75%). Baseline characteristics of women with and without isthmocele were similar. Conversely, the clinical pregnancy rate (adjusted OR 0.31, 95% CI 0.13 to 0.72) and live birth rate (adjusted OR 038, 95% CI 0.17 to 0.86) were significantly lower among affected women. No associations between specific sonographic defect characteristics and IVF outcome could be identified. CONCLUSIONSCaesarean scar defects are common among women with a history of caesarean section requiring IVF. The presence of these lesions may reduce the chance of success of the procedure. How common are caesarean scar defects (isthmocele) among patients who have had previous caesarean delivery undergoing IVF for secondary infertility? Does the presence of isthmocele affect the chances of success of IVF? In this cohort study, women referred to an Italian public assisted reproduction centre between January 2016 and April 2021 were retrospectively reviewed. Women with a history of caesarean delivery and an indication for IVF were selected. On the basis of the local policy, all patients with a history of caesarean section underwent saline contrast sonography (SCS). Sonographic evaluation was standardized. One hundred and forty-four women were eligible, of whom 22 declined SCS and eight decided to delay pregnancy seeking. Overall, 114 women were available for data analysis. Seventy-six women were diagnosed with caesarean scar defects, corresponding to a prevalence of 67% (95% CI 58 to 75%). Baseline characteristics of women with and without isthmocele were similar. Conversely, the clinical pregnancy rate (adjusted OR 0.31, 95% CI 0.13 to 0.72) and live birth rate (adjusted OR 038, 95% CI 0.17 to 0.86) were significantly lower among affected women. No associations between specific sonographic defect characteristics and IVF outcome could be identified. Caesarean scar defects are common among women with a history of caesarean section requiring IVF. The presence of these lesions may reduce the chance of success of the procedure. |
| ArticleNumber | 103240 |
| Author | Somigliana, Edgardo Benaglia, Laura Mensi, Laura Filippi, Francesca Vercellini, Paolo Alagna, Federica Reschini, Marco Riccaboni, Alessandra |
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| Keywords | in vitro fertilization isthmocele infertility caesarean section caesarean scar defect |
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| References | Tulandi, Cohen (bib0014) 2016 Sep-Oct; 23 Cai, Pan, Xia, Liang, Yang (bib0006) 2022 Mar 26 Lawrenz, Melado, Garrido, Coughlan, Markova, Fatemi (bib0011) 2020 Jan 1; 35 Vissers, Sluckin, van Driel-Delprat, Schats, Groot, Lambalk, Twisk, Huirne (bib0016) 2020 Mar 27; 35 Wang, Yin, Xu, Qi, Wang, Yang (bib0018) 2017; 37 Abdou, Ammar (bib0001) 2018; 23 Akman, Erden, Bahceci (bib0002) 2005 Apr; 20 Benaglia, Busnelli, Biancardi, Vegetti, Reschini, Vercellini, Somigliana (bib0004) 2018 Jul; 37 Gurol-Urganci I., Bou-Antoun S., Lim C.P., Cromwell D.A., Mahmood T.A., Templeton A., van der Meulen J.H. Impact of Caesarean section on subsequent fertility: a systematic review and meta-analysis. Hum. Reprod. 2013 Jul;28(7):1943-52. doi . Wang, Wang, Lu, Liu, Diao (bib0017) 2022 May 23; 13 Bij de Vaate, van der Voet, Naji, Witmer, Veersema, Brölmann, Bourne, Huirne (bib0005) 2014 Apr; 43 Jordans, de Leeuw, Stegwee, Amso, Barri-Soldevila, van den Bosch, Bourne, Brölmann, Donnez, Dueholm, Hehenkamp, Jastrow, Jurkovic, Mashiach, Naji, Streuli, Timmerman, van der Voet, Huirne (bib0010) 2019 Jan; 53 Harjee, Khinda, Bedaiwy (bib0009) 2021 Jul; 28 Diao, Gao, Zhang, Wang, Zhang, Han, Du, Luo (bib0007) 2021 Jul 6; 21 Strandell, Lindhard, Waldenström, Thorburn (bib0013) 2001 Nov; 16 van den Tweel, Klijn, Diaz de Pool, van der Westerlaken, Louwe (bib0015) 2022 Feb; 25 Asoglu, Celik, Ozturk, Cavkaytar, Bahceci (bib0003) 2021 May; 28 Somigliana, Sarais, Reschini, Ferrari, Makieva, Cermisoni, Paffoni, Papaleo, Vigano (bib0012) 2021 Sep; 225 van den Tweel (10.1016/j.rbmo.2023.05.012_bib0015) 2022; 25 Benaglia (10.1016/j.rbmo.2023.05.012_bib0004) 2018; 37 Wang (10.1016/j.rbmo.2023.05.012_bib0017) 2022; 13 Akman (10.1016/j.rbmo.2023.05.012_bib0002) 2005; 20 Cai (10.1016/j.rbmo.2023.05.012_bib0006) 2022 Harjee (10.1016/j.rbmo.2023.05.012_bib0009) 2021; 28 Bij de Vaate (10.1016/j.rbmo.2023.05.012_bib0005) 2014; 43 Diao (10.1016/j.rbmo.2023.05.012_bib0007) 2021; 21 Abdou (10.1016/j.rbmo.2023.05.012_bib0001) 2018; 23 Strandell (10.1016/j.rbmo.2023.05.012_bib0013) 2001; 16 Asoglu (10.1016/j.rbmo.2023.05.012_bib0003) 2021; 28 Somigliana (10.1016/j.rbmo.2023.05.012_bib0012) 2021; 225 Tulandi (10.1016/j.rbmo.2023.05.012_bib0014) 2016; 23 10.1016/j.rbmo.2023.05.012_bib0008 Vissers (10.1016/j.rbmo.2023.05.012_bib0016) 2020; 35 Jordans (10.1016/j.rbmo.2023.05.012_bib0010) 2019; 53 Lawrenz (10.1016/j.rbmo.2023.05.012_bib0011) 2020; 35 Wang (10.1016/j.rbmo.2023.05.012_bib0018) 2017; 37 |
| References_xml | – volume: 28 start-page: 1113 year: 2021 May end-page: 1120 ident: bib0003 article-title: Impact of Isthmocele on Assisted Reproductive Treatment Outcomes: An Age-matched Retrospective Study publication-title: J. Minim. Invasive. Gynecol. contributor: fullname: Bahceci – volume: 43 start-page: 372 year: 2014 Apr end-page: 382 ident: bib0005 article-title: Prevalence, potential risk factors for development and symptoms related to the presence of uterine niches following Cesarean section: systematic review publication-title: Ultrasound. Obstet. Gynecol. contributor: fullname: Huirne – volume: 35 start-page: 89 year: 2020 Jan 1 end-page: 99 ident: bib0011 article-title: Isthmocele and ovarian stimulation for IVF: considerations for a reproductive medicine specialist publication-title: Hum. Reprod. contributor: fullname: Fatemi – volume: 225 start-page: 283.e1 year: 2021 Sep end-page: 283.e10 ident: bib0012 article-title: Single oral dose of vitamin D publication-title: Am. J. Obstet. Gynecol. contributor: fullname: Vigano – volume: 35 start-page: 595 year: 2020 Mar 27 end-page: 604 ident: bib0016 article-title: Reduced pregnancy and live birth rates after in vitro fertilization in women with previous Caesarean section: a retrospective cohort study publication-title: Hum. Reprod. contributor: fullname: Huirne – volume: 23 start-page: 893 year: 2016 Sep-Oct end-page: 902 ident: bib0014 article-title: Emerging Manifestations of Cesarean Scar Defect in Reproductive-aged Women publication-title: J. Minim. Invasive. Gynecol. contributor: fullname: Cohen – volume: 21 start-page: 487 year: 2021 Jul 6 ident: bib0007 article-title: Caesarean section defects may affect pregnancy outcomes after in vitro fertilization-embryo transfer: a retrospective study publication-title: BMC Pregnancy Childbirth contributor: fullname: Luo – volume: 28 start-page: 1291 year: 2021 Jul end-page: 1302 ident: bib0009 article-title: Reproductive Outcomes Following Surgical Management for Isthmoceles: A Systematic Review publication-title: J. Minim. Invasive. Gynecol. contributor: fullname: Bedaiwy – volume: 37 start-page: 77 year: 2018 Jul end-page: 84 ident: bib0004 article-title: Oocyte retrieval difficulties in women with ovarian endometriomas publication-title: Reprod. Biomed. Online. contributor: fullname: Somigliana – volume: 53 start-page: 107 year: 2019 Jan end-page: 115 ident: bib0010 article-title: Sonographic examination of uterine niche in non-pregnant women: a modified Delphi procedure publication-title: Ultrasound. Obstet. Gynecol. contributor: fullname: Huirne – volume: 23 start-page: 505 year: 2018 end-page: 509 ident: bib0001 article-title: Role of hysteroscopic repair of caesarean scar defect in women with secondary infertility publication-title: Middle. East. Fertile. Soc. J. contributor: fullname: Ammar – volume: 25 start-page: 93 year: 2022 Feb end-page: 98 ident: bib0015 article-title: Previous caesarean section is associated with lower subsequent in vitro fertilization live birth rates publication-title: Hum. Fertil. (Camb) contributor: fullname: Louwe – year: 2022 Mar 26 ident: bib0006 article-title: Intra-cavitary fluid resulted from caesarean section but not isthmocele compromised clinical pregnancy after IVF/ICSI treatment publication-title: Arch. Gynecol. Obstet. contributor: fullname: Yang – volume: 13 year: 2022 May 23 ident: bib0017 article-title: Pregnancy and Perinatal Outcomes of Patients With Prior Cesarean Section After a Single Embryo Transfer in IVF/ICSI: A Retrospective Cohort Study publication-title: Front. Endocrinol. (Lausanne) contributor: fullname: Diao – volume: 37 start-page: 922 year: 2017 end-page: 927 ident: bib0018 article-title: Reproductive outcomes in women with prior cesarean section undergoing in vitro fertilization: A retrospective case-control study publication-title: J Huazhong Univ Sci Technolog Med Sci contributor: fullname: Yang – volume: 20 start-page: 906 year: 2005 Apr end-page: 909 ident: bib0002 article-title: Endometrial fluid visualized through ultrasonography during ovarian stimulation in IVF cycles impairs the outcome in tubal factor, but not PCOS, patients publication-title: Hum. Reprod. contributor: fullname: Bahceci – volume: 16 start-page: 2403 year: 2001 Nov end-page: 2410 ident: bib0013 article-title: Hydrosalpinx and IVF outcome: cumulative results after salpingectomy in a randomized controlled trial publication-title: Hum. Reprod. contributor: fullname: Thorburn – volume: 225 start-page: 283.e1 issue: 3 year: 2021 ident: 10.1016/j.rbmo.2023.05.012_bib0012 article-title: Single oral dose of vitamin D3 supplementation prior to in vitro fertilization and embryo transfer in normal weight women: the SUNDRO randomized controlled trial publication-title: Am. J. Obstet. Gynecol. doi: 10.1016/j.ajog.2021.04.234 contributor: fullname: Somigliana – volume: 23 start-page: 893 issue: 6 year: 2016 ident: 10.1016/j.rbmo.2023.05.012_bib0014 article-title: Emerging Manifestations of Cesarean Scar Defect in Reproductive-aged Women publication-title: J. Minim. Invasive. Gynecol. doi: 10.1016/j.jmig.2016.06.020 contributor: fullname: Tulandi – volume: 35 start-page: 595 issue: 3 year: 2020 ident: 10.1016/j.rbmo.2023.05.012_bib0016 article-title: Reduced pregnancy and live birth rates after in vitro fertilization in women with previous Caesarean section: a retrospective cohort study publication-title: Hum. Reprod. doi: 10.1093/humrep/dez295 contributor: fullname: Vissers – volume: 25 start-page: 93 issue: 1 year: 2022 ident: 10.1016/j.rbmo.2023.05.012_bib0015 article-title: Previous caesarean section is associated with lower subsequent in vitro fertilization live birth rates publication-title: Hum. Fertil. (Camb) doi: 10.1080/14647273.2019.1696990 contributor: fullname: van den Tweel – volume: 53 start-page: 107 issue: 1 year: 2019 ident: 10.1016/j.rbmo.2023.05.012_bib0010 article-title: Sonographic examination of uterine niche in non-pregnant women: a modified Delphi procedure publication-title: Ultrasound. Obstet. Gynecol. doi: 10.1002/uog.19049 contributor: fullname: Jordans – year: 2022 ident: 10.1016/j.rbmo.2023.05.012_bib0006 article-title: Intra-cavitary fluid resulted from caesarean section but not isthmocele compromised clinical pregnancy after IVF/ICSI treatment publication-title: Arch. Gynecol. Obstet. doi: 10.1007/s00404-022-06436-0 contributor: fullname: Cai – volume: 20 start-page: 906 issue: 4 year: 2005 ident: 10.1016/j.rbmo.2023.05.012_bib0002 article-title: Endometrial fluid visualized through ultrasonography during ovarian stimulation in IVF cycles impairs the outcome in tubal factor, but not PCOS, patients publication-title: Hum. Reprod. doi: 10.1093/humrep/deh737 contributor: fullname: Akman – volume: 35 start-page: 89 issue: 1 year: 2020 ident: 10.1016/j.rbmo.2023.05.012_bib0011 article-title: Isthmocele and ovarian stimulation for IVF: considerations for a reproductive medicine specialist publication-title: Hum. Reprod. doi: 10.1093/humrep/dez241 contributor: fullname: Lawrenz – volume: 37 start-page: 922 year: 2017 ident: 10.1016/j.rbmo.2023.05.012_bib0018 article-title: Reproductive outcomes in women with prior cesarean section undergoing in vitro fertilization: A retrospective case-control study publication-title: J Huazhong Univ Sci Technolog Med Sci contributor: fullname: Wang – ident: 10.1016/j.rbmo.2023.05.012_bib0008 doi: 10.1093/humrep/det130 – volume: 28 start-page: 1291 issue: 7 year: 2021 ident: 10.1016/j.rbmo.2023.05.012_bib0009 article-title: Reproductive Outcomes Following Surgical Management for Isthmoceles: A Systematic Review publication-title: J. Minim. Invasive. Gynecol. doi: 10.1016/j.jmig.2021.03.012 contributor: fullname: Harjee – volume: 43 start-page: 372 issue: 4 year: 2014 ident: 10.1016/j.rbmo.2023.05.012_bib0005 article-title: Prevalence, potential risk factors for development and symptoms related to the presence of uterine niches following Cesarean section: systematic review publication-title: Ultrasound. Obstet. Gynecol. doi: 10.1002/uog.13199 contributor: fullname: Bij de Vaate – volume: 37 start-page: 77 issue: 1 year: 2018 ident: 10.1016/j.rbmo.2023.05.012_bib0004 article-title: Oocyte retrieval difficulties in women with ovarian endometriomas publication-title: Reprod. Biomed. Online. doi: 10.1016/j.rbmo.2018.03.020 contributor: fullname: Benaglia – volume: 13 year: 2022 ident: 10.1016/j.rbmo.2023.05.012_bib0017 article-title: Pregnancy and Perinatal Outcomes of Patients With Prior Cesarean Section After a Single Embryo Transfer in IVF/ICSI: A Retrospective Cohort Study publication-title: Front. Endocrinol. (Lausanne) contributor: fullname: Wang – volume: 16 start-page: 2403 issue: 11 year: 2001 ident: 10.1016/j.rbmo.2023.05.012_bib0013 article-title: Hydrosalpinx and IVF outcome: cumulative results after salpingectomy in a randomized controlled trial publication-title: Hum. Reprod. doi: 10.1093/humrep/16.11.2403 contributor: fullname: Strandell – volume: 23 start-page: 505 year: 2018 ident: 10.1016/j.rbmo.2023.05.012_bib0001 article-title: Role of hysteroscopic repair of caesarean scar defect in women with secondary infertility publication-title: Middle. East. Fertile. Soc. J. doi: 10.1016/j.mefs.2018.06.005 contributor: fullname: Abdou – volume: 21 start-page: 487 issue: 1 year: 2021 ident: 10.1016/j.rbmo.2023.05.012_bib0007 article-title: Caesarean section defects may affect pregnancy outcomes after in vitro fertilization-embryo transfer: a retrospective study publication-title: BMC Pregnancy Childbirth doi: 10.1186/s12884-021-03955-7 contributor: fullname: Diao – volume: 28 start-page: 1113 issue: 5 year: 2021 ident: 10.1016/j.rbmo.2023.05.012_bib0003 article-title: Impact of Isthmocele on Assisted Reproductive Treatment Outcomes: An Age-matched Retrospective Study publication-title: J. Minim. Invasive. Gynecol. doi: 10.1016/j.jmig.2020.10.002 contributor: fullname: Asoglu |
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| Title | Prevalence and clinical effect of caesarean scar defects in women undergoing IVF |
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