Determination of 27 amino acids’ levels in seminal plasma of asthenospermia and oligospermia patients and diagnostic value analysis

• Published in: Journal of pharmaceutical and biomedical analysis Vol. 184; p. 113211
• Main Authors: Deng, Mingjie, Lin, Feiyan, Zhou, Caiping, Chen, Yuyan, Xuan, Leijie, Wang, Hongzhe, Feng, Tiantian, Hu, Lufeng
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 30.05.2020
• Subjects: Adult; Amino Acids - analysis; Asthenozoospermia; Asthenozoospermia - diagnosis; Biomarkers - analysis; Chromatography, High Pressure Liquid - methods; Diagnosis; Healthy Volunteers; Humans; Male; Oligospermia; Oligospermia - diagnosis; Semen - chemistry; Semen Analysis - methods; Seminal fluid; Tandem Mass Spectrometry - methods; UPLC-MS/MS; Young Adult; UPLC-MS/MS; Seminal fluid; Diagnosis; Asthenozoospermia; Oligospermia

•27 amino acids determined by an UPLC-MS/MS method within 3 min were developed.•27 amino acids levels in seminal plasma of male infertility patients were analyzed.•Glutamic acid, tyrosine, aspartic acid, proline and tryptophan related to each other.•Amino acids had diagnostic value for asthenospermi...