Synthesis and initial in vitro evaluation of PSMA-targeting ligands with a modified aromatic moiety at the lysine ε-nitrogen atom - Zyk, Nikolai Y.; Ber, Anton P.; Nimenko, Ekaterina A.; Shafikov, Radik R.; Evteev, Sergei A.; Petrov, Stanislav A.; Uspenskaya, Anastasia A.; Dashkova, Natalia S.; Ivanenkov, Yan A.; Skvortsov, Dmitry A.; Beloglazkina, Elena K.; Majouga, Alexander G.; et al. (Bioorganic & medicinal chemistry letters, 2022)
Keywords: Chemistry; Chemistry, Medicinal; Chemistry, Organic; Drug delivery; Life Sciences & Biomedicine; Ligands; Pharmacology & Pharmacy; Physical Sciences; Prostate cancer; Prostate-specific membrane antigen; Science & Technology; Sulfo-Cy5; DUPA; PyBOP; DIPEA; Drug delivery; DCL; TFA; DCM; Prostate-specific membrane antigen; 2-PMPA; HOBt; Ligands; HBTU; GCPII; DMF; Prostate cancer; NAAG; Sulfo-Cy5; 2-MPPA; TIPS; DESIGN; GLUTAMATE CARBOXYPEPTIDASE-II; INHIBITORS; MEMBRANE ANTIGEN PSMA; PRECLINICAL EVALUATION