DNA methylation affects the lifespan of honey bee (Apis mellifera L.) workers – Evidence for a regulatory module that involves vitellogenin expression but is independent of juvenile hormone function

• Published in: Insect biochemistry and molecular biology Vol. 92; pp. 21 - 29
• Main Authors: Cardoso-Júnior, Carlos A.M., Guidugli-Lazzarini, Karina R., Hartfelder, Klaus
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.01.2018
• Subjects: DNA methyltransferase; Epigenetics; Lifespan; Longevity; Vitellogenin; Epigenetics; DNA methyltransferase; Longevity; Vitellogenin; Lifespan

The canonic regulatory module for lifespan of honey bee (Apis mellifera) workers involves a mutual repressor relationship between juvenile hormone (JH) and vitellogenin (Vg). Compared to vertebrates, however, little is known about a possible role of epigenetic factors. The full genomic repertoire of...