Prolonged orocecal transit time enhances serum bile acids through bacterial overgrowth, contributing factor to gallstone disease

• Published in: Journal of clinical gastroenterology Vol. 48; no. 4; p. 365
• Main Authors: Kaur, Jaspreet, Rana, Satya V, Gupta, Rajesh, Gupta, Vikas, Sharma, Surendra K, Dhawan, Devinder K
• Format: Journal Article
• Language: English
• Published: United States 01.04.2014
• Subjects: Adolescent; Adult; Bile Acids and Salts - blood; Breath Tests; Case-Control Studies; Female; Gallstones - etiology; Gallstones - pathology; Gastrointestinal Motility; Gastrointestinal Transit; Humans; Intestine, Small - microbiology; Linear Models; Male; Middle Aged; Prospective Studies; Young Adult
• ISSN: 1539-2031
• DOI: 10.1097/MCG.0b013e3182a14fba

Gallstones (GS) are associated with slow intestinal transit but the effect of altered transit time on physiological changes in gastrointestinal tract among GS patients is poorly understood. To investigate the association of gallstone disease with change in intestinal motility and how motility alters...