Short-chain fatty acid levels in stools of patients with inflammatory bowel disease are lower than those in healthy subjects

• Published in: European journal of gastroenterology & hepatology Vol. 36; no. 7; p. 890
• Main Authors: Ozturk, Ozlem, Celebi, Gurkan, Duman, Umut Goktan, Kupcuk, Erhan, Uyanik, Metin, Sertoglu, Erdim
• Format: Journal Article
• Language: English
• Published: England 01.07.2024
• Subjects: Acetic Acid - analysis; Acetic Acid - metabolism; Adult; Butyric Acid - analysis; Butyric Acid - metabolism; Case-Control Studies; Colitis, Ulcerative - metabolism; Colitis, Ulcerative - microbiology; Crohn Disease - metabolism; Diet; Fatty Acids, Volatile - analysis; Fatty Acids, Volatile - metabolism; Feces - chemistry; Feces - microbiology; Female; Gas Chromatography-Mass Spectrometry; Gastrointestinal Microbiome; Humans; Male; Middle Aged; Propionates - analysis; Propionates - metabolism; Young Adult

Short-chain fatty acids (SCFAs) are produced when the microbiota in the large intestine cause fermentation of dietary carbohydrates and fibers. These fatty acids constitute the primary energy source of colon mucosa cells and have a protective effect in patients suffering from inflammatory bowel dise...