Analysis of the Duodenal Microbiome in Autistic Individuals: Association With Carbohydrate Digestion

• Published in: Journal of pediatric gastroenterology and nutrition Vol. 64; no. 5; p. e110
• Main Authors: Kushak, Rafail I, Winter, Harland S, Buie, Timothy M, Cox, Stephen B, Phillips, Caleb D, Ward, Naomi L
• Format: Journal Article
• Language: English
• Published: United States 01.05.2017
• Subjects: Adolescent; Autistic Disorder - complications; Autistic Disorder - metabolism; Autistic Disorder - microbiology; Biomarkers - metabolism; Carbohydrate Metabolism - physiology; Case-Control Studies; Diet; Digestion; Disaccharidases - metabolism; Duodenum - metabolism; Duodenum - microbiology; Dysbiosis - diagnosis; Dysbiosis - etiology; Dysbiosis - metabolism; Female; Gastrointestinal Microbiome; Humans; Intestinal Mucosa - metabolism; Intestinal Mucosa - microbiology; Linear Models; Male; Microbiota; Retrospective Studies

There is evidence that symptoms of maldigestion or malabsorption in autistic individuals are related to changes in the indigenous microbiota. Analysis of colonic bacteria has revealed microbial dysbiosis in children with autism; however, characteristics of the duodenal microbiome are not well descri...