Lower Coated-Platelet Levels Are Associated With Increased Mortality After Spontaneous Intracerebral Hemorrhage

• Published in: Stroke (1970) Vol. 46; no. 7; pp. 1819 - 1825
• Main Authors: Prodan, Calin I., Stoner, Julie A., Dale, George L.
• Format: Journal Article
• Language: English
• Published: United States American Heart Association, Inc 01.07.2015
• Subjects: Adult; Aged; Aged, 80 and over; Blood Platelets - metabolism; Cerebral Hemorrhage - blood; Cerebral Hemorrhage - drug therapy; Cerebral Hemorrhage - mortality; Collagen - administration & dosage; Female; Humans; Male; Middle Aged; Mortality - trends; Platelet Function Tests - mortality; Prospective Studies; Risk Factors; Thrombin - administration & dosage; thrombosis; stroke; platelets; hemorrhage

BACKGROUND AND PURPOSE—Coated-platelets are highly procoagulant platelets observed on dual-agonist stimulation with collagen and thrombin. Coated-platelet levels are decreased in patients with spontaneous intracerebral hemorrhage when compared with controls and inversely correlated with bleed volume...