ISSLS Prize Winner: Vertebral Endplate (Modic) Change is an Independent Risk Factor for Episodes of Severe and Disabling Low Back Pain

• Published in: Spine (Philadelphia, Pa. 1976) Vol. 40; no. 15; p. 1187
• Main Authors: Määttä, Juhani H, Wadge, Sam, MacGregor, Alex, Karppinen, Jaro, Williams, Frances M K
• Format: Journal Article
• Language: English
• Published: United States 01.08.2015
• Subjects: Adult; Aged; Female; Humans; Intervertebral Disc Degeneration - complications; Intervertebral Disc Degeneration - pathology; Interviews as Topic; Longitudinal Studies; Low Back Pain - epidemiology; Low Back Pain - etiology; Lumbar Vertebrae - pathology; Magnetic Resonance Imaging; Male; Middle Aged; Registries; Risk Factors; Severity of Illness Index

Longitudinal cohort study of twins representative of the general population. To assess the relationship between Modic change (MC) and severe, disabling low back pain (LBP), features of intervertebral disc degeneration (DD) and incident MC during 10-year follow-up. MC describes vertebral endplate and...