A Prospective, Open-label Study to Assess the Safety, Tolerability and Efficacy of Anidulafungin in the Treatment of Invasive Candidiasis in Children 2 to <18 Years of Age

• Published in: The Pediatric infectious disease journal Vol. 38; no. 3; p. 275
• Main Authors: Roilides, Emmanuel, Carlesse, Fabianne, Leister-Tebbe, Heidi, Conte, Umberto, Yan, Jean L, Liu, Ping, Tawadrous, Margaret, Aram, Jalal A, Queiroz-Telles, Flavio
• Format: Journal Article
• Language: English
• Published: United States 01.03.2019
• Subjects: Administration, Intravenous; Adolescent; Anidulafungin - therapeutic use; Antifungal Agents - therapeutic use; Candida - drug effects; Candidiasis, Invasive - drug therapy; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Internationality; Male; Prospective Studies; Treatment Outcome

Treatment with an echinocandin is recommended as first-line therapy for patients with invasive candidiasis (ICC) including candidemia. Little is known about the efficacy and safety of anidulafungin in children with ICC. Eligible patients with ICC 2 to <18 years old were enrolled into this prospec...