Biometric, histomorphometric, and biochemical profile in atorvastatin calcium treatment of female rats with dexamethasone-induced osteoporosis

• Published in: Revista brasileira de ortopedia Vol. 53; no. 5; pp. 607 - 613
• Main Authors: Ferreira Junior, Davilson Bragine, Pizziolo, Virgínia Ramos, Oliveira, Tânia Toledo de, Matta, Sérgio Luis Pinto da, Píccolo, Mayra Soares, Queiroz, José Humberto de
• Format: Journal Article
• Language: English
• Published: Brazil Elsevier Editora Ltda 01.09.2018; Elsevier; Sociedade Brasileira de Ortopedia e Traumatologia; Thieme Revinter Publicações Ltda
• Subjects: Alendronate; Alendronato; Alkaline phosphatase; Bone histomorphometry; Difosfonatos; Diphosphonates; Fosfatase alcalina; Glicocorticóide; Glucocorticoid; Histomorfometria óssea; Original; ORTHOPEDICS; Alkaline phosphatase; Bone histomorphometry; Difosfonatos; Fosfatase alcalina; Alendronate; Diphosphonates; Histomorfometria óssea; Glucocorticoid; Glicocorticóide; Alendronato

To assess the effects of atorvastatin calcium in the treatment of dexamethasone-induced osteoporosis. Osteoporosis induction consisted of the administration of an intramuscular dose of 7.5mg/kg of body weight of dexamethasone, once a week for four weeks, except for the control animals (G1). The anim...