Comparative effects of ionic and nonionic iodinated low-osmolar contrast media on platelet function with the PFA-100 (platelet function analyzer)

• Published in: Investigative radiology Vol. 36; no. 5; p. 276
• Main Authors: D'Anglemont De Tassigny, A, IDéE, J M, Corot, A C
• Format: Journal Article
• Language: English
• Published: United States 01.05.2001
• Subjects: Adult; Animals; Contrast Media - pharmacology; Female; Humans; Iohexol - pharmacology; Ioxaglic Acid - pharmacology; Male; Osmolar Concentration; Platelet Aggregation - drug effects; Swine; Triiodobenzoic Acids - pharmacology

This study was designed to (1) compare the effects of ionic (ioxaglate) and nonionic (iodixanol and iohexol) iodinated low-osmolar contrast media (CM) on platelet function in human whole blood by using the new PFA-100trade mark, a "platelet function analyzer"; (2) determine the animal spec...