Can Virtual Contrast Enhancement in Brain MRI Replace Gadolinium?: A Feasibility Study

• Published in: Investigative radiology Vol. 54; no. 10; p. 653
• Main Authors: Kleesiek, Jens, Morshuis, Jan Nikolas, Isensee, Fabian, Deike-Hofmann, Katerina, Paech, Daniel, Kickingereder, Philipp, Köthe, Ullrich, Rother, Carsten, Forsting, Michael, Wick, Wolfgang, Bendszus, Martin, Schlemmer, Heinz-Peter, Radbruch, Alexander
• Format: Journal Article
• Language: English
• Published: United States 01.10.2019
• Subjects: Adult; Bayes Theorem; Brain - diagnostic imaging; Brain Neoplasms - diagnostic imaging; Feasibility Studies; Female; Gadolinium; Humans; Image Enhancement - methods; Magnetic Resonance Imaging - methods; Male; Sensitivity and Specificity; Signal-To-Noise Ratio

Gadolinium-based contrast agents (GBCAs) have become an integral part in daily clinical decision making in the last 3 decades. However, there is a broad consensus that GBCAs should be exclusively used if no contrast-free magnetic resonance imaging (MRI) technique is available to reduce the amount of...