The Efficacy of Massage in Reducing Nodule Formation After Poly-L-Lactic Acid Administration for Facial Volume Loss: A Randomized, Evaluator-Blinded Clinical Trial

• Published in: Dermatologic surgery Vol. 42; no. 11; p. 1266
• Main Authors: Wu, Douglas C, Goldman, Mitchel P
• Format: Journal Article
• Language: English
• Published: United States 01.11.2016
• Subjects: Adult; Cosmetic Techniques; Face; Humans; Injections, Intradermal; Injections, Subcutaneous; Lipodystrophy - drug therapy; Massage; Middle Aged; Polyesters - administration & dosage; Polyesters - therapeutic use; Prospective Studies; Treatment Outcome

The risk of nodule formation following poly-L-lactic acid (PLLA) injections for facial volume loss is well known. Traditionally, post-treatment massage according to the 5-5-5 rule (5 times per day for 5 minutes for 5 days) has been applied to mitigate this risk. However, such a regimen may be onerou...