A Nationwide Prospective Clinical Trial on Active Surveillance in Patients With Non-intraabdominal Desmoid-type Fibromatosis: The GRAFITI Trial

• Published in: Annals of surgery Vol. 277; no. 4; p. 689
• Main Authors: Schut, Anne-Rose W, Timbergen, Milea J M, van Broekhoven, Danique L M, van Dalen, Thijs, van Houdt, Winan J, Bonenkamp, Johannes J, Sleijfer, Stefan, Grunhagen, Dirk J, Verhoef, Cornelis
• Format: Journal Article
• Language: English
• Published: United States 01.04.2023
• Subjects: Adult; beta Catenin - genetics; Fibromatosis, Aggressive - genetics; Fibromatosis, Aggressive - therapy; Humans; Mutation; Prospective Studies; Watchful Waiting

To assess tumor behavior and the efficacy of active surveillance (AS) in patients with desmoid-type fibromatosis (DTF). AS is recommended as initial management for DTF patients. Prospective data regarding the results of AS are lacking. In this multicenter prospective cohort study (NTR4714), adult pa...