The Potential Impact of Renin-Angiotensin System Inhibitors on Cancer Survival and Recurrence: A Systemic Review and Meta-Analysis

• Published in: Journal of cardiovascular pharmacology Vol. 85; no. 1; p. 35
• Main Authors: Fatima, Kaneez, Ellahi, Aayat, Adil, Mariam, Kashif, Haider, Uzair, Muhammad, Ashraf, Naela, Barolia, Mehak, Hyder, Mujtaba, Nakhuda, Areeba, Ayub, Michelle, Butt, Sofia Jamil, Rashid, Ahmed Mustafa
• Format: Journal Article
• Language: English
• Published: United States 01.01.2025
• Subjects: Angiotensin Receptor Antagonists - adverse effects; Angiotensin Receptor Antagonists - therapeutic use; Angiotensin-Converting Enzyme Inhibitors - adverse effects; Angiotensin-Converting Enzyme Inhibitors - therapeutic use; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasms - drug therapy; Neoplasms - mortality; Neoplasms - pathology; Progression-Free Survival; Renin-Angiotensin System - drug effects; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome

Renin-angiotensin system inhibitors (RASis), specifically angiotensin-converting enzyme inhibitors (ACEis) and angiotensin II receptor blockers (ARBs), are widely used antihypertensives. Their impact on the prognostic outcomes among patients with cancer has been subject to scrutiny and debate. The a...