β-Catenin in Canine Skin: Immunohistochemical Pattern of Expression in Normal Skin and Cutaneous Epithelial Tumours

• Published in: Journal of comparative pathology Vol. 145; no. 2; pp. 138 - 147
• Main Authors: Bongiovanni, L., Malatesta, D., Brachelente, C., D’Egidio, S., Della Salda, L.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.08.2011
• Subjects: Animals; beta Catenin - metabolism; dog; Dogs; Female; Immunohistochemistry; Male; Neoplasms, Adnexal and Skin Appendage - metabolism; Neoplasms, Adnexal and Skin Appendage - pathology; skin; Skin - metabolism; Skin - pathology; Skin Neoplasms - metabolism; Skin Neoplasms - pathology; tumour; β-catenin; skin; β-catenin; dog; tumour

In normal adult skin, β-catenin is a structural component of the intercellular junction and the Wnt/β-catenin pathway plays a key role in the regulation of cutaneous homeostasis, particularly in the maintenance of hair follicle stem cells. No data are available on the expression pattern of β-catenin...