A survey on computational models for predicting protein–protein interactions

• Published in: Briefings in bioinformatics Vol. 22; no. 5
• Main Authors: Hu, Lun, Wang, Xiaojuan, Huang, Yu-An, Hu, Pengwei, You, Zhu-Hong
• Format: Journal Article
• Language: English
• Published: England 02.09.2021
• Subjects: performance evaluation; protein–protein interaction; biological databases; computational prediction models

Proteins interact with each other to play critical roles in many biological processes in cells. Although promising, laboratory experiments usually suffer from the disadvantages of being time-consuming and labor-intensive. The results obtained are often not robust and considerably uncertain. Due rece...