Carboxylesterase3 (Ces3) Interacts with Bone Morphogenetic Protein 11 and Promotes Differentiation of Osteoblasts via Smad1/5/9 Pathway

• Published in: Biotechnology and bioprocess engineering Vol. 27; no. 1; pp. 1 - 16
• Main Authors: Mukherjee, Sulagna, Park, Jong Pil, Yun, Jong Won
• Format: Journal Article
• Language: English
• Published: Seoul The Korean Society for Biotechnology and Bioengineering 01.02.2022; 한국생물공학회
• Subjects: adipocytes; biochemical pathways; bioprocessing; Biotechnology; bone formation; bone morphogenetic proteins; Chemistry; Chemistry and Materials Science; computer simulation; crosslinking; drug development; enzymes; gene targeting; Industrial and Production Engineering; liver; osteoblasts; Research Paper; 생물공학; Smad 1/5/9; BMP11; differentiation; osteoblasts; Ces3

Ces3 is a lipolytic enzyme predominantly present in liver and adipocytes, with recent reports of its presence in skeletal muscles, as well. A cross-linking study to understand the various interacting proteins involved in bone-adipose axis could provide novel targets for drug development. We explored...