Herpes simplex virus reactivation in patients with COVID-19 and acute respiratory distress syndrome: a prospective cohort study

• Published in: Antiviral therapy Vol. 27; no. 1; p. 135965352110686
• Main Authors: Chiesa, Alessandro F, Pallanza, Micol, Martinetti, Gladys, Lanzi, Fabio, Previsdomini, Marco, Pagnamenta, Alberto, Elzi, Luigia
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.02.2022; International Medical Press
• Subjects: Antiviral agents; Catheters; Cohort analysis; Coronaviruses; COVID-19; Herpes simplex; Herpes viruses; Laboratories; Mechanical ventilation; Patient positioning; Patients; Regression analysis; Respiratory distress syndrome; Risk factors; Severe acute respiratory syndrome coronavirus 2; Steroid hormones; Ventilation; Ventilator-associated pneumonia; Ventilators; Viruses

Background There is a paucity of data about the occurrence and risk factors of herpes simplex virus (HSV) reactivation among patients with severe COVID-19 presenting with acute respiratory distress syndrome (ARDS). Methods We performed a nested case-control study among a cohort of SARS-CoV-2 infecte...