Thrombotic thrombocytopenic purpura after a dogbite

A man bitten by a pet dog had fulminant thrombotic thrombocytopenic purpura within 72 hours. Rhabdomyolysis was severe and acute anuric renal failure was present. The suspected causative agent was Pastuerella multocida or clostridia with possible endotoxemia, though early treatment precluded a defin...

Full description

Saved in:
Bibliographic Details
Published inSouthern medical journal (Birmingham, Ala.) Vol. 73; no. 5; p. 676
Main Authors Mars, D R, Knochel, J P, Cotton, J R, Fuller, T J
Format Journal Article
LanguageEnglish
Published United States 01.05.1980
Subjects
Animals
Bites and Stings - complications
Dogs
Humans
Hydrocortisone - therapeutic use
Male
Methylprednisolone - therapeutic use
Middle Aged
Penicillins - therapeutic use
Prednisolone - therapeutic use
Purpura, Thrombotic Thrombocytopenic - etiology
Purpura, Thrombotic Thrombocytopenic - therapy
Renal Dialysis
Splenectomy
Online AccessGet more information

Cover

More Information
Summary:A man bitten by a pet dog had fulminant thrombotic thrombocytopenic purpura within 72 hours. Rhabdomyolysis was severe and acute anuric renal failure was present. The suspected causative agent was Pastuerella multocida or clostridia with possible endotoxemia, though early treatment precluded a definitive diagnosis. The patient responded dramatically to a combined therapeutic approach of antibiotics, steroids, splenectomy, and supportive hemodialysis.
ISSN:0038-4348
DOI:10.1097/00007611-198005000-00039