Magnetic resonance imaging, microangiography, and histology in a rat model of primary liver cancer

• Published in: Investigative radiology Vol. 27; no. 9; p. 689
• Main Authors: Ni, Y, Marchal, G, van Damme, B, van Hecke, P, Michiels, J, Zhang, X, Yu, J, Baert, A L
• Format: Journal Article
• Language: English
• Published: United States 01.09.1992
• Subjects: Animals; Contrast Media; Diethylnitrosamine; Disease Models, Animal; Liver - diagnostic imaging; Liver - pathology; Liver Neoplasms, Experimental - chemically induced; Liver Neoplasms, Experimental - diagnosis; Liver Neoplasms, Experimental - pathology; Magnetic Resonance Imaging - instrumentation; Magnetic Resonance Imaging - methods; Male; Microradiography - methods; Rats; Rats, Wistar

N-nitrosodiethylamine is able to induce various benign and malignant liver lesions in rats with a high success rate and a low mortality rate. It provides a more appropriate model that better simulates the various lesions occurring in patients than the usual model of tumor implantations. Hepatic carc...