Partial inertion as basis of safety for pharmaceutical operations involving highly ignition sensitive powders and modeling combustion properties as a function of oxygen concentration

• Published in: Process safety progress Vol. 40; no. 1
• Main Authors: Toth, Michael, Orella, Charles, Roth, Megan, Muzzio, Dan, Fisher, Elizabeth, Vickery, Thomas, Bachert, Don, Stone, Shane, Bader, Josh
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.03.2021; John Wiley and Sons, Limited
• Subjects: Adiabatic; Combustion; Economic models; Explosions; fire and explosion analysis; Flame temperature; hazards evaluation; Ignition; Materials handling; Modelling; Oxygen; Pharmaceuticals; Protection systems; risk assessment; Safety; safety management; Toxic materials; Toxicity testing

Pharmaceutical operations often require inertion or other suitable explosion protection systems when handling highly ignition sensitive materials. Regulating bodies typically require full inertion, which may be difficult and expensive to maintain. This work measured the influence of oxygen concentra...