Sustained perturbation in functional connectivity induced by cold pain

• Published in: European journal of pain Vol. 24; no. 9; pp. 1850 - 1861
• Main Authors: Makovac, Elena, Dipasquale, Ottavia, Jackson, Jade B., Medina, Sonia, O'Daly, Owen, O'Muircheartaigh, Jonathan, Lara Rubio, Alfonso, Williams, Steven C. R., McMahon, Stephen B., Howard, Matthew A.
• Format: Journal Article
• Language: English
• Published: England 01.10.2020
• Subjects: Brain Mapping; Chronic Pain - diagnostic imaging; Humans; Magnetic Resonance Imaging; Neural Pathways - diagnostic imaging; Prefrontal Cortex - diagnostic imaging

Background Functional connectivity (FC) perturbations have been reported in multiple chronic pain phenotypes, but the nature of reported changes varies between cohorts and may relate to the consequences of living with chronic‐pain related comorbidities, such as anxiety and depression. Healthy volunt...