A small yet comprehensive subset of human experimental pain models emerging from correlation analysis with a clinical quantitative sensory testing protocol in healthy subjects

• Published in: European journal of pain Vol. 20; no. 5; p. 777
• Main Authors: Lötsch, J, Dimova, V, Ultsch, A, Lieb, I, Zimmermann, M, Geisslinger, G, Oertel, B G
• Format: Journal Article
• Language: English
• Published: England 01.05.2016
• Subjects: Adolescent; Adult; Analgesics - therapeutic use; Clinical Protocols; Electric Stimulation; Female; Healthy Volunteers; Hot Temperature; Humans; Male; Models, Theoretical; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Nontherapeutic Human Experimentation; Pain - drug therapy; Pain Measurement; Pain Threshold; Pressure; Young Adult

Picturing the complexity of pain in human experimental settings has increased the predictivity for clinical pain but requires increasingly complex test batteries. This raises problems in studies in which time is objectively limited, for example by the course of action of an analgesic drug. We addres...