Optimisation of quantitative brain diffusion-relaxation MRI acquisition protocols with physics-informed machine learning

• Published in: Medical image analysis Vol. 94; p. 103134
• Main Authors: Planchuelo-Gómez, Álvaro, Descoteaux, Maxime, Larochelle, Hugo, Hutter, Jana, Jones, Derek K., Tax, Chantal M.W.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.05.2024
• Subjects: Brain; Diffusion-relaxation; Machine learning; Quantitative MRI; Brain; Quantitative MRI; Diffusion-relaxation; Machine learning
• ISSN: 1361-8415; 1361-8423; 1361-8423
• DOI: 10.1016/j.media.2024.103134

Diffusion-relaxation MRI aims to extract quantitative measures that characterise microstructural tissue properties such as orientation, size, and shape, but long acquisition times are typically required. This work proposes a physics-informed learning framework to extract an optimal subset of diffusi...