Clinical signs, risk factors, and outcomes associated with bromide toxicosis (bromism) in dogs with idiopathic epilepsy

• Published in: Journal of the American Veterinary Medical Association Vol. 234; no. 11; pp. 1425 - 1431
• Main Authors: Rossmeisl, John H. Jr, Inzana, Karen D
• Format: Journal Article
• Language: English
• Published: United States 01.06.2009
• Subjects: Animals; anticonvulsants; Anticonvulsants - administration & dosage; Anticonvulsants - adverse effects; Anticonvulsants - therapeutic use; bromides; Bromides - administration & dosage; Bromides - adverse effects; Bromides - therapeutic use; bromism; complications; disease severity; dog diseases; Dog Diseases - chemically induced; Dogs; dosage; dose response; Dose-Response Relationship, Drug; drug excretion; drug therapy; epidemiological studies; epilepsy; Epilepsy - drug therapy; Epilepsy - veterinary; etiology; pathogenesis; poisoning; potassium bromide; Potassium Compounds - administration & dosage; Potassium Compounds - adverse effects; Potassium Compounds - therapeutic use; Retrospective Studies; Risk Factors; signs and symptoms (animals and humans); sodium bromide; Sodium Compounds - administration & dosage; Sodium Compounds - adverse effects; Sodium Compounds - therapeutic use

To evaluate clinical signs, risk factors, and outcomes associated with bromide toxicosis (bromism) in dogs with idiopathic epilepsy treated with potassium or sodium bromide. Retrospective case-control study. 83 clinically ill epileptic dogs with (cases; n = 31) and without (controls; 52) bromism. Me...