Influence of triamcinolone intravitreal injection on retinochoroidal healing processes

• Published in: Experimental eye research Vol. 84; no. 6; pp. 1081 - 1089
• Main Authors: Dot, C., Behar-Cohen, F., BenEzra, D., Doat, M., Jonet, L., May, F., Jeanny, J.C.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.06.2007
• Subjects: Animals; Anti-Inflammatory Agents - pharmacology; Anti-Inflammatory Agents - therapeutic use; Apoptosis - drug effects; Cell Proliferation - drug effects; choroidal neovascularization; Choroidal Neovascularization - etiology; Choroidal Neovascularization - prevention & control; corticosteroids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Glucocorticoids - pharmacology; Glucocorticoids - therapeutic use; In Situ Nick-End Labeling; Laser Coagulation; laser photocoagulation; Mice; Mice, Inbred C57BL; retinal remodeling; triamcinolone; Triamcinolone Acetonide - pharmacology; Triamcinolone Acetonide - therapeutic use; wound healing; Wound Healing - drug effects; retinal remodeling; wound healing; laser photocoagulation; corticosteroids; choroidal neovascularization; triamcinolone

To analyze the effects of triamcinolone intravitreal injection on the wound healing processes after argon laser retinal photocoagulation, wild type C57BL/6J mice, 8–12 weeks old underwent a standard argon laser photocoagulation protocol. After pentobarbital anesthesia and pupil dilatation, argon las...