An hypothesis about genome structures in mammalian polyploid cells based on a new concept that genome is fractal of six hierarchies

• Published in: Medical hypotheses Vol. 66; no. 2; pp. 337 - 344
• Main Author: Fujikawa-Yamamoto, Kohzaburo
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 2006
• Subjects: Animals; Chromosomes, Human; DNA - chemistry; Genome; Genomic Imprinting; Humans; Polyploidy

A new model for the spatial configurations of DNA is proposed to solve the problem of DNA loss in mammalian polyploid cells. The ordinary concept that chromosomes are situated independently in nuclei cannot account well for the DNA loss in polyploid cells. A new concept about the DNA configurations...