Cognitive deficits in spinocerebellar ataxia type 1, 2, and 3

• Published in: Journal of neurology Vol. 250; no. 2; pp. 207 - 211
• Main Authors: BÜRK, K, GLOBAS, C, BÖSCH, S, KLOCKGETHER, T, ZÜHLKE, C, DAUM, I, DICHGANS, J
• Format: Journal Article
• Language: English
• Published: Berlin Springer 01.02.2003; Springer Nature B.V
• Subjects: Age of Onset; Aging - physiology; Biological and medical sciences; Cognition Disorders - etiology; Cognition Disorders - psychology; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Disease Progression; Female; Humans; Male; Medical sciences; Memory - physiology; Middle Aged; Neurology; Neuropsychological Tests; Psychomotor Performance - physiology; Space Perception - physiology; Spinocerebellar Ataxias - complications; Spinocerebellar Ataxias - psychology; Human; Nervous system diseases; Cognitive disorder; cognition; Neuropsychological test; Exploration; Psychometrics; cerebellum; Cerebral disorder; Genetic disease; Spinocerebellar heredodegeneration; executive dysfunction; Central nervous system disease; Degenerative disease; Spinal cord disease; spinocerebellar ataxia

Cognitive impairment was studied in distinct types of spinocerebellar ataxia (SCA): eleven SCA1, 14 SCA2, and 11 SCA3 individuals and 8 age- and IQ- matched controls. All were submitted to a neuropsychological test battery that comprised tests for IQ, attention, executive function, verbal and visuos...