Expression dynamics of the poly-γ-glutamic acid biosynthesis genes of Bacillus subtilis in response to glucose and glutamic acid-A pilot study

• Published in: FEMS microbiology letters Vol. 365; no. 22
• Main Authors: Tiwari, Deepika Pandey, Chatterjee, Poonam Mishra, Rotti, Harish, Chand, Bipin, Raval, Ritu, Dubey, Ashok Kumar
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.11.2018
• Subjects: Acids; Bacillus subtilis; Biosynthesis; DNA microarrays; enzymes; Gene expression; gene expression regulation; Genes; Glucose; Glutamic acid; microarray technology; Microbiology; operon; poly-γ-Glutamic acid; polyglutamic acid

Poly-γ-glutamic acid (PGA) is biosynthesized by various Bacillus species through PGA synthetase, encoded by the PGA operon comprised of the ywsC and ywtABC genes. Due to the minimal available knowledge, understanding the expression pattern of PGA operon genes is pivotal. In this study, the effect of...