microRNA-430b targets scavenger receptor class B member 1 (scarb1) and inhibits coloration and carotenoid synthesis in koi carp (Cyprinus carpio L.)

• Published in: Aquaculture Vol. 546; p. 737334
• Main Authors: Tian, Xue, Peng, Nian-nian, Ma, Xiao, Wu, Li-min, Shi, Xi, Liu, Hui-fen, Song, Hong-mei, Wu, Qi-sheng, Meng, Xiao-lin, Li, Xue-jun
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 15.01.2022
• Subjects: aquaculture; Carotenoid metabolism; carotenoids; chromatophores; color; Cyprinus carpio; koi; Koi carp; mesoderm; metabolism; miR-430; phenotype; pigmentation; scarb1; Skin color; RS; de; E; nt; H; bco2; bl; K; M; scarb1; WF; sc; BSA; SE; Skin color; WR; WS; Koi carp; KH; dph; ML; WW; PBS; ss; scarb1–2; RSC; WSC; qRT-PCR; 3′-UTR; ep; PVDF; CT; SDS-PAGE; gtpch1; s; pre-miR-430; spr; RF; miR-430; mitf; xdh; Carotenoid metabolism

In teleost fishes, miR-430 has several paralogs and is widely required for mesoderm formation and gonad development. However, the functions of miR-430 in skin pigmentation have not been completely elucidated. To understand the functions of miR-430 in color formation, we analyzed the conserved charac...