Current perspectives on familial Mediterranean fever

• Published in: Current opinion in infectious diseases Vol. 22; no. 3; p. 309
• Main Authors: Guz, Galip, Kanbay, Mehmet, Ozturk, M Akif
• Format: Journal Article
• Language: English
• Published: United States 01.06.2009
• Subjects: Amyloid - metabolism; Biomedical Research - trends; Cytoskeletal Proteins - genetics; Cytoskeletal Proteins - physiology; Familial Mediterranean Fever - genetics; Familial Mediterranean Fever - immunology; Familial Mediterranean Fever - pathology; Humans; Inflammation - pathology; Pyrin

The gene responsible for familial Mediterranean Fever (FMF), MEditerranean FeVer (MEFV), was identified two decades ago; however, only recent studies have shed light on its pathogenesis. This review focuses on recent studies that have led us to more fully understand FMF pathogenesis. The vast majori...