Finding the Rhythm of Sudden Cardiac Death: New Opportunities Using Induced Pluripotent Stem Cell–Derived Cardiomyocytes - Sallam, Karim; Li, Yingxin; Sager, Philip T.; Houser, Steven R.; Wu, Joseph C. (Circulation research, 2015)
Keywords: Animals; Cardiovascular Agents - pharmacology; Cell Differentiation - drug effects; Cells, Cultured; Clinical Trials as Topic - methods; Computer Simulation; Death, Sudden, Cardiac - etiology; Disease Models, Animal; Drug Evaluation, Preclinical - methods; Electrophysiology - methods; Forecasting; Heart Diseases - complications; Heart Diseases - genetics; Heart Diseases - pathology; Humans; Induced Pluripotent Stem Cells - cytology; Ion Channels - physiology; Long QT Syndrome - genetics; Long QT Syndrome - pathology; Long QT Syndrome - physiopathology; Models, Cardiovascular; Myocytes, Cardiac - cytology; Myocytes, Cardiac - drug effects; Myocytes, Cardiac - physiology; Organ Culture Techniques; Patch-Clamp Techniques - methods; Tachycardia, Ventricular - genetics; Tachycardia, Ventricular - pathology; Tachycardia, Ventricular - physiopathology; death, sudden, cardiac; induced pluripotent stem cells; cardiovascular diseases; drug discovery