Injection of ROS‐Responsive Hydrogel Loaded with Basic Fibroblast Growth Factor into the Pericardial Cavity for Heart Repair

• Published in: Advanced functional materials Vol. 31; no. 15
• Main Authors: Li, Zhenhua, Zhu, Dashuai, Hui, Qi, Bi, Jianing, Yu, Bingjie, Huang, Zhen, Hu, Shiqi, Wang, Zhenzhen, Caranasos, Thomas, Rossi, Joseph, Li, Xiaokun, Cheng, Ke, Wang, Xiaojie
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc 01.04.2021
• Subjects: bFGF; Fibroblasts; Fibrosis; Growth factors; Heart attacks; Heart diseases; heart repair; Hydrogels; Injuries; intrapericardial delivery; Ischemia; Materials science; Myocardial infarction; Myocardium; pericardial cavity; Polyvinyl alcohol; ROS responsive hydrogels

Myocardial infarction, among other ischemic heart diseases, is the major cause of mortality and morbidity for patients who have heart diseases. Timely reperfusion of the ischemic myocardium is the most effective way to treat myocardial infarction. However, blood reperfusion to the ischemic tissues l...