Perioperative cardiac arrest: an evolutionary analysis of the intra-operative cardiac arrest incidence in tertiary centers in Brazil
Great changes in medicine have taken place over the last 25 years worldwide. These changes in technologies, patient risks, patient profile, and laws regulating the medicine have impacted the incidence of cardiac arrest. It has been postulated that the incidence of intraoperative cardiac arrest has d...
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Published in | Brazilian journal of anesthesiology (Elsevier) Vol. 66; no. 2; pp. 176 - 182 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
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Brazil
Elsevier Editora Ltda
01.03.2016
Sociedade Brasileira de Anestesiologia Elsevier |
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Abstract | Great changes in medicine have taken place over the last 25 years worldwide. These changes in technologies, patient risks, patient profile, and laws regulating the medicine have impacted the incidence of cardiac arrest. It has been postulated that the incidence of intraoperative cardiac arrest has decreased over the years, especially in developed countries. The authors hypothesized that, as in the rest of the world, the incidence of intraoperative cardiac arrest is decreasing in Brazil, a developing country.
The aim of this study was to search the literature to evaluate the publications that relate the incidence of intraoperative cardiac arrest in Brazil and analyze the trend in the incidence of intraoperative cardiac arrest.
There were 4 articles that met our inclusion criteria, resulting in 204,072 patients undergoing regional or general anesthesia in two tertiary and academic hospitals, totalizing 627 cases of intraoperative cardiac arrest. The mean intraoperative cardiac arrest incidence for the 25 years period was 30.72:10,000 anesthesias. There was a decrease from 39:10,000 anesthesias to 13:10,000 anesthesias in the analyzed period, with the related lethality from 48.3% to 30.8%. Also, the main causes of anesthesia-related cause of mortality changed from machine malfunction and drug overdose to hypovolemia and respiratory causes.
There was a clear reduction in the incidence of intraoperative cardiac arrest in the last 25 years in Brazil. This reduction is seen worldwide and might be a result of multiple factors, including new laws regulating the medicine in Brazil, incorporation of technologies, better human development level of the country, and better patient care.
Nos últimos 25 anos ocorreram grandes mudanças na medicina em todo o mundo. Essas mudanças de tecnologias, riscos do paciente, perfil do paciente e leis que regulam medicamentos tiveram impacto na incidência de parada cardíaca (PC). Postula-se que a incidência de parada cardíaca intraoperatória (PCI) tem diminuído ao longo dos anos, especialmente em países desenvolvidos. A nossa hipótes foi que, como no resto do mundo, a incidência de PCI está diminuindo no Brasil, um país em desenvolvimento.
O objetivo deste estudo foi pesquisar e avaliar na literatura as publicações que relacionam a incidência de PCI no Brasil e analisar a tendência na incidência de PCI.
Descobrimos quatro artigos que atenderam os critérios de inclusão, resultando em 204.072 pacientes submetidos à anestesia regional ou geral em dois hospitais terciários e acadêmicos, totalizando 627 casos de PCI. A média de incidência de PCI para o período de 25 anos foi de 30,72:10.000 anestesias. Houve uma diminuição de 39:10.000 anestesias para 13:10.000 anestesias no período analisado, com letalidade relacionada de 48,3% para 30,8%. Além disso, as principais causas de mortalidade relacionadas à anestesia mudaram de mau funcionamento de máquinas e overdose de medicamentos para hipovolemia e causas respiratórias.
Houve uma clara redução na incidência de PCI nos últimos 25 anos no Brasil. Essa redução é observada em todo o mundo e pode ser o resultado de vários fatores, incluindo novas leis que regulam medicamentos no Brasil, incorporação de tecnologias, melhor nível de desenvolvimento humano do país e melhor assistência ao paciente. |
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AbstractList | Background: Great changes in medicine have taken place over the last 25 years worldwide. These changes in technologies, patient risks, patient profile, and laws regulating the medicine have impacted the incidence of cardiac arrest. It has been postulated that the incidence of intraoperative cardiac arrest has decreased over the years, especially in developed countries. The authors hypothesized that, as in the rest of the world, the incidence of intraoperative cardiac arrest is decreasing in Brazil, a developing country. Objectives: The aim of this study was to search the literature to evaluate the publications that relate the incidence of intraoperative cardiac arrest in Brazil and analyze the trend in the incidence of intraoperative cardiac arrest. Contents: There were 4 articles that met our inclusion criteria, resulting in 204,072 patients undergoing regional or general anesthesia in two tertiary and academic hospitals, totalizing 627 cases of intraoperative cardiac arrest. The mean intraoperative cardiac arrest incidence for the 25 years period was 30.72:10,000 anesthesias. There was a decrease from 39:10,000 anesthesias to 13:10,000 anesthesias in the analyzed period, with the related lethality from 48.3% to 30.8%. Also, the main causes of anesthesia-related cause of mortality changed from machine malfunction and drug overdose to hypovolemia and respiratory causes. Conclusions: There was a clear reduction in the incidence of intraoperative cardiac arrest in the last 25 years in Brazil. This reduction is seen worldwide and might be a result of multiple factors, including new laws regulating the medicine in Brazil, incorporation of technologies, better human development level of the country, and better patient care. Resumo: Justificativa: Nos últimos 25 anos ocorreram grandes mudanças na medicina em todo o mundo. Essas mudanças de tecnologias, riscos do paciente, perfil do paciente e leis que regulam medicamentos tiveram impacto na incidência de parada cardíaca (PC). Postula-se que a incidência de parada cardíaca intraoperatória (PCI) tem diminuído ao longo dos anos, especialmente em países desenvolvidos. A nossa hipótes foi que, como no resto do mundo, a incidência de PCI está diminuindo no Brasil, um país em desenvolvimento. Objetivos: O objetivo deste estudo foi pesquisar e avaliar na literatura as publicações que relacionam a incidência de PCI no Brasil e analisar a tendência na incidência de PCI. Conteúdo: Descobrimos quatro artigos que atenderam os critérios de inclusão, resultando em 204.072 pacientes submetidos à anestesia regional ou geral em dois hospitais terciários e acadêmicos, totalizando 627 casos de PCI. A média de incidência de PCI para o período de 25 anos foi de 30,72:10.000 anestesias. Houve uma diminuição de 39:10.000 anestesias para 13:10.000 anestesias no período analisado, com letalidade relacionada de 48,3% para 30,8%. Além disso, as principais causas de mortalidade relacionadas à anestesia mudaram de mau funcionamento de máquinas e overdose de medicamentos para hipovolemia e causas respiratórias. Conclusões: Houve uma clara redução na incidência de PCI nos últimos 25 anos no Brasil. Essa redução é observada em todo o mundo e pode ser o resultado de vários fatores, incluindo novas leis que regulam medicamentos no Brasil, incorporação de tecnologias, melhor nível de desenvolvimento humano do país e melhor assistência ao paciente. Keywords: Intra-operative complications, Heart arrest, Cardiopulmonary resuscitation, Anesthesia, Palavras-chave: Complicações intraoperatórias, Parada cardíaca, Reanimação cardiopulmonar, Anestesia Great changes in medicine have taken place over the last 25 years worldwide. These changes in technologies, patient risks, patient profile, and laws regulating the medicine have impacted the incidence of cardiac arrest. It has been postulated that the incidence of intraoperative cardiac arrest has decreased over the years, especially in developed countries. The authors hypothesized that, as in the rest of the world, the incidence of intraoperative cardiac arrest is decreasing in Brazil, a developing country. The aim of this study was to search the literature to evaluate the publications that relate the incidence of intraoperative cardiac arrest in Brazil and analyze the trend in the incidence of intraoperative cardiac arrest. There were 4 articles that met our inclusion criteria, resulting in 204,072 patients undergoing regional or general anesthesia in two tertiary and academic hospitals, totalizing 627 cases of intraoperative cardiac arrest. The mean intraoperative cardiac arrest incidence for the 25 years period was 30.72:10,000 anesthesias. There was a decrease from 39:10,000 anesthesias to 13:10,000 anesthesias in the analyzed period, with the related lethality from 48.3% to 30.8%. Also, the main causes of anesthesia-related cause of mortality changed from machine malfunction and drug overdose to hypovolemia and respiratory causes. There was a clear reduction in the incidence of intraoperative cardiac arrest in the last 25 years in Brazil. This reduction is seen worldwide and might be a result of multiple factors, including new laws regulating the medicine in Brazil, incorporation of technologies, better human development level of the country, and better patient care. ABSTRACT BACKGROUND: Great changes in medicine have taken place over the last 25 years worldwide. These changes in technologies, patient risks, patient profile, and laws regulating the medicine have impacted the incidence of cardiac arrest. It has been postulated that the incidence of intraoperative cardiac arrest has decreased over the years, especially in developed countries. The authors hypothesized that, as in the rest of the world, the incidence of intraoperative cardiac arrest is decreasing in Brazil, a developing country. OBJECTIVES: The aim of this study was to search the literature to evaluate the publications that relate the incidence of intraoperative cardiac arrest in Brazil and analyze the trend in the incidence of intraoperative cardiac arrest. CONTENTS: There were 4 articles that met our inclusion criteria, resulting in 204,072 patients undergoing regional or general anesthesia in two tertiary and academic hospitals, totalizing 627 cases of intraoperative cardiac arrest. The mean intraoperative cardiac arrest incidence for the 25 years period was 30.72:10,000 anesthesias. There was a decrease from 39:10,000 anesthesias to 13:10,000 anesthesias in the analyzed period, with the related lethality from 48.3% to 30.8%. Also, the main causes of anesthesia-related cause of mortality changed from machine malfunction and drug overdose to hypovolemia and respiratory causes. CONCLUSIONS: There was a clear reduction in the incidence of intraoperative cardiac arrest in the last 25 years in Brazil. This reduction is seen worldwide and might be a result of multiple factors, including new laws regulating the medicine in Brazil, incorporation of technologies, better human development level of the country, and better patient care. Great changes in medicine have taken place over the last 25 years worldwide. These changes in technologies, patient risks, patient profile, and laws regulating the medicine have impacted the incidence of cardiac arrest. It has been postulated that the incidence of intraoperative cardiac arrest has decreased over the years, especially in developed countries. The authors hypothesized that, as in the rest of the world, the incidence of intraoperative cardiac arrest is decreasing in Brazil, a developing country. The aim of this study was to search the literature to evaluate the publications that relate the incidence of intraoperative cardiac arrest in Brazil and analyze the trend in the incidence of intraoperative cardiac arrest. There were 4 articles that met our inclusion criteria, resulting in 204,072 patients undergoing regional or general anesthesia in two tertiary and academic hospitals, totalizing 627 cases of intraoperative cardiac arrest. The mean intraoperative cardiac arrest incidence for the 25 years period was 30.72:10,000 anesthesias. There was a decrease from 39:10,000 anesthesias to 13:10,000 anesthesias in the analyzed period, with the related lethality from 48.3% to 30.8%. Also, the main causes of anesthesia-related cause of mortality changed from machine malfunction and drug overdose to hypovolemia and respiratory causes. There was a clear reduction in the incidence of intraoperative cardiac arrest in the last 25 years in Brazil. This reduction is seen worldwide and might be a result of multiple factors, including new laws regulating the medicine in Brazil, incorporation of technologies, better human development level of the country, and better patient care. Nos últimos 25 anos ocorreram grandes mudanças na medicina em todo o mundo. Essas mudanças de tecnologias, riscos do paciente, perfil do paciente e leis que regulam medicamentos tiveram impacto na incidência de parada cardíaca (PC). Postula-se que a incidência de parada cardíaca intraoperatória (PCI) tem diminuído ao longo dos anos, especialmente em países desenvolvidos. A nossa hipótes foi que, como no resto do mundo, a incidência de PCI está diminuindo no Brasil, um país em desenvolvimento. O objetivo deste estudo foi pesquisar e avaliar na literatura as publicações que relacionam a incidência de PCI no Brasil e analisar a tendência na incidência de PCI. Descobrimos quatro artigos que atenderam os critérios de inclusão, resultando em 204.072 pacientes submetidos à anestesia regional ou geral em dois hospitais terciários e acadêmicos, totalizando 627 casos de PCI. A média de incidência de PCI para o período de 25 anos foi de 30,72:10.000 anestesias. Houve uma diminuição de 39:10.000 anestesias para 13:10.000 anestesias no período analisado, com letalidade relacionada de 48,3% para 30,8%. Além disso, as principais causas de mortalidade relacionadas à anestesia mudaram de mau funcionamento de máquinas e overdose de medicamentos para hipovolemia e causas respiratórias. Houve uma clara redução na incidência de PCI nos últimos 25 anos no Brasil. Essa redução é observada em todo o mundo e pode ser o resultado de vários fatores, incluindo novas leis que regulam medicamentos no Brasil, incorporação de tecnologias, melhor nível de desenvolvimento humano do país e melhor assistência ao paciente. BACKGROUNDGreat changes in medicine have taken place over the last 25 years worldwide. These changes in technologies, patient risks, patient profile, and laws regulating the medicine have impacted the incidence of cardiac arrest. It has been postulated that the incidence of intraoperative cardiac arrest has decreased over the years, especially in developed countries. The authors hypothesized that, as in the rest of the world, the incidence of intraoperative cardiac arrest is decreasing in Brazil, a developing country.OBJECTIVESThe aim of this study was to search the literature to evaluate the publications that relate the incidence of intraoperative cardiac arrest in Brazil and analyze the trend in the incidence of intraoperative cardiac arrest.CONTENTSThere were 4 articles that met our inclusion criteria, resulting in 204,072 patients undergoing regional or general anesthesia in two tertiary and academic hospitals, totalizing 627 cases of intraoperative cardiac arrest. The mean intraoperative cardiac arrest incidence for the 25 years period was 30.72:10,000 anesthesias. There was a decrease from 39:10,000 anesthesias to 13:10,000 anesthesias in the analyzed period, with the related lethality from 48.3% to 30.8%. Also, the main causes of anesthesia-related cause of mortality changed from machine malfunction and drug overdose to hypovolemia and respiratory causes.CONCLUSIONSThere was a clear reduction in the incidence of intraoperative cardiac arrest in the last 25 years in Brazil. This reduction is seen worldwide and might be a result of multiple factors, including new laws regulating the medicine in Brazil, incorporation of technologies, better human development level of the country, and better patient care. |
Author | Sá Malbouisson, Luiz Marcelo do Prado Nuzzi, Rafael Ximenes Carmona, Maria José Carvalho Aranha, Gustavo Fabio Auler, José Otávio Costa da Luz, Vinicius Fernando Gonzalez, Maria Margarita Castro Vane, Matheus Fachini |
AuthorAffiliation | Universidade de São Paulo |
AuthorAffiliation_xml | – name: Universidade de São Paulo |
Author_xml | – sequence: 1 givenname: Matheus Fachini surname: Vane fullname: Vane, Matheus Fachini email: mfvane@uol.com.br organization: Discipline of Anesthesiology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil – sequence: 2 givenname: Rafael Ximenes surname: do Prado Nuzzi fullname: do Prado Nuzzi, Rafael Ximenes organization: Discipline of Anesthesiology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil – sequence: 3 givenname: Gustavo Fabio surname: Aranha fullname: Aranha, Gustavo Fabio organization: Discipline of Anesthesiology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil – sequence: 4 givenname: Vinicius Fernando surname: da Luz fullname: da Luz, Vinicius Fernando organization: Discipline of Anesthesiology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil – sequence: 5 givenname: Luiz Marcelo surname: Sá Malbouisson fullname: Sá Malbouisson, Luiz Marcelo organization: Discipline of Anesthesiology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil – sequence: 6 givenname: Maria Margarita Castro surname: Gonzalez fullname: Gonzalez, Maria Margarita Castro organization: Heart Institue (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil – sequence: 7 givenname: José Otávio Costa surname: Auler fullname: Auler, José Otávio Costa organization: Discipline of Anesthesiology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil – sequence: 8 givenname: Maria José Carvalho surname: Carmona fullname: Carmona, Maria José Carvalho organization: Discipline of Anesthesiology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil |
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Keywords | Heart arrest Intra-operative complications Cardiopulmonary resuscitation Parada cardíaca Reanimação cardiopulmonar Anesthesia Complicações intraoperatórias Anestesia Intra‐operative complications |
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Society of Thoracic Surgeons publication-title: Ann Thorac Surg contributor: fullname: Peterson – volume: 15 start-page: 816 year: 1999 end-page: 822 ident: bib0075 article-title: Risk factors and outcome in European cardiac surgery: analysis of the EuroSCORE multinational database of 19030 patients publication-title: Eur J Cardiothorac Surg contributor: fullname: Michel – volume: 28 start-page: 505 year: 2011 end-page: 515 ident: bib0025 article-title: Pre-arrest predictors of failure to survive after in-hospital cardiopulmonary resuscitation: a meta-analysis publication-title: Fam Pract contributor: fullname: Afonso – volume: 33 start-page: 336 year: 1986 end-page: 344 ident: bib0135 article-title: Complications associated with anaesthesia – a prospective survey in France publication-title: Can Anaesth Soc J contributor: fullname: Hatton – volume: 117 start-page: 1018 year: 2012 end-page: 1026 ident: bib0060 article-title: Intraoperative cardiac arrests in adults undergoing noncardiac surgery: incidence, risk factors, and survival outcome publication-title: Anesthesiology contributor: fullname: Jordan – volume: 32 start-page: 653 year: 1988 end-page: 664 ident: bib0045 article-title: Cardiac arrest during anaesthesia. 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mortality and morbidity over a 5-year period in 2,363,038 patients in Japan publication-title: Acta Anaesthesiol Scand – year: 2006 publication-title: Brazilian Federal Council of Medicine Resolution – volume: 30 start-page: 91 year: 2012 end-page: 103 article-title: Prognosis in cardiac arrest publication-title: Emerg Med Clin N Am – volume: 99 start-page: 259 year: 2003 end-page: 269 article-title: Predictors of survival following cardiac arrest in patients undergoing noncardiac surgery a study of 518,294 patients at a tertiary referral center publication-title: Anesthesiology – volume: 265 start-page: 2815 year: 1991 end-page: 2820 article-title: Incidence and characteristics of preventable iatrogenic cardiac arrests publication-title: JAMA – volume: 49 start-page: 257 year: 1999 end-page: 262 article-title: Cardiac arrest during anesthesia at a tertiary teaching hospital (1988 to 1996) publication-title: Rev Bras Anestesiol – volume: 96 start-page: 569 year: 2006 end-page: 575 article-title: Perioperative cardiac arrest a study of 53,718 anaesthetics over 9 yr from a Brazilian teaching hospital publication-title: Br J Anaesth – year: 2012 publication-title: World Development Indicators 2012 – volume: 14 start-page: 269 year: 2008 end-page: 274 article-title: Cardiac arrest during anesthesia publication-title: Curr Opin Crit Care – volume: 131 start-page: 309 year: 2013 end-page: 314 article-title: Frequency of intraoperative cardiac arrest and medium-term survival publication-title: Sao Paulo Med J – volume: 15 start-page: 816 year: 1999 end-page: 822 article-title: Risk factors and outcome in European cardiac surgery: analysis of the EuroSCORE multinational database of 19030 patients publication-title: Eur J Cardiothorac Surg – volume: 97 start-page: 108 year: 2002 end-page: 115 article-title: Anesthetic-related cardiac arrest and its mortality a report covering 72,959 anesthetics over 10 years from a US teaching hospital publication-title: Anesthesiology – volume: 5 start-page: 287 year: 1986 end-page: 294 article-title: Arret cardiaque pendant l'anesthesie et la periode de reveil Donnees de l'enquete INSERM 1978-1982 [Cardiac arrest during anesthesia and the recovery period publication-title: Data from the INSERM survey 1978-1982]. Ann Fr Anesth Réanim – volume: 148 start-page: 14 year: 2013 end-page: 21 article-title: Cardiac arrest among surgical patients an analysis of incidence, patient characteristics, and outcomes in ACSNSQIP publication-title: JAMA Surg – volume: 130 start-page: 15 year: 1995 end-page: 18 article-title: Improved survival after intraoperative cardiac arrest in noncardiac surgical patients publication-title: Arch Surg – volume: 33 start-page: 336 year: 1986 end-page: 344 article-title: Complications associated with anaesthesia - a prospective survey in France publication-title: Can Anaesth Soc J – volume: 86 start-page: 1165 year: 1998 end-page: 1170 article-title: The influence of an aging surgical population on the anesthesia workload a ten-year survey publication-title: Anesth Analg – volume: 88 start-page: 613 year: 2005 end-page: 622 article-title: Surveillance of anesthetic related complications at Srinagarind Hospital, Khon Kaen University, Thailand publication-title: J Med Assoc Thai – volume: 1 start-page: 305 year: 1984 end-page: 318 article-title: Cardiac arrest related to anaesthesia a prospective survey in France (1978-1982) publication-title: Eur J Anaesthesiol – volume: 380 start-page: 1075 year: 2012 end-page: 1081 article-title: Perioperative and anaesthetic-related mortality in developed and developing countries a systematic review and meta-analysis publication-title: Lancet – volume: 3 start-page: 354 year: 1991 end-page: 357 article-title: Decreasing frequency of anesthetic cardiac arrests publication-title: J Clin Anesth – year: 1993 publication-title: Brazilian Federal Council of Medicine Resolution 1.363/93 – volume: 6 start-page: 91 year: 1993 end-page: 101 article-title: In-hospital cardiopulmonary resuscitation a 30-year review publication-title: J Am Board Fam Pract – volume: 32 start-page: 653 year: 1988 end-page: 664 article-title: Cardiac arrest during anaesthesia A computer-aided study in 250,543 anaesthetics publication-title: Acta Anaesthesiol Scand – volume: 117 start-page: 1018 year: 2012 end-page: 1026 article-title: Intraoperative cardiac arrests in adults undergoing noncardiac surgery incidence, risk factors, and survival outcome publication-title: Anesthesiology – volume: 73 start-page: 480 year: 2002 end-page: 489 article-title: A decade of change-risk profiles and outcomes for isolated coronary artery bypass grafting procedures, 1990-1999: a report from the STS National Database Committee and the Duke Clinical Research Institute. Society of Thoracic Surgeons publication-title: Ann Thorac Surg – volume: 28 start-page: 505 year: 2011 end-page: 515 article-title: Pre-arrest predictors of failure to survive after in-hospital cardiopulmonary resuscitation a metaanalysis publication-title: Fam Pract – volume: 35 start-page: 731 year: 2000 end-page: 738 article-title: Outcomes of cardiac surgery in patients > or = 80 years results from the National Cardiovascular Network publication-title: J Am Coll Cardiol – volume: 36 start-page: 149 year: 1986 end-page: 158 article-title: Cardiac arrest during anesthesia in a multicenter hospital a descriptive study publication-title: Rev Bras Anestesiol |
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Snippet | Great changes in medicine have taken place over the last 25 years worldwide. These changes in technologies, patient risks, patient profile, and laws regulating... BACKGROUNDGreat changes in medicine have taken place over the last 25 years worldwide. These changes in technologies, patient risks, patient profile, and laws... ABSTRACT BACKGROUND: Great changes in medicine have taken place over the last 25 years worldwide. These changes in technologies, patient risks, patient... Background: Great changes in medicine have taken place over the last 25 years worldwide. These changes in technologies, patient risks, patient profile, and... |
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SubjectTerms | Anestesia Anesthesia ANESTHESIOLOGY Cardiopulmonary resuscitation Complicações intraoperatórias Heart arrest Intra-operative complications Parada cardíaca Reanimação cardiopulmonar |
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Title | Perioperative cardiac arrest: an evolutionary analysis of the intra-operative cardiac arrest incidence in tertiary centers in Brazil |
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