Dual‐Stimuli‐Responsive Gut Microbiota‐Targeting Berberine‐CS/PT‐NPs Improved Metabolic Status in Obese Hamsters

• Published in: Advanced functional materials Vol. 29; no. 14
• Main Authors: Guo, Hui‐Hui, Ma, Chen, Zheng, Wen‐Sheng, Luo, Yang, Li, Cong, Li, Xiao‐Lin, Ma, Xiao‐Lei, Feng, Chen‐Lin, Zhang, Ting‐Ting, Han, Yan‐Xing, Luo, Zhi‐Gang, Zhan, Yun, Li, Rui, Wang, Lu‐Lu, Jiang, Jian‐Dong
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc 04.04.2019
• Subjects: Bacteria; berberine; Colon; colon specific; Disorders; Drug delivery systems; gut microbiota; Hamsters; Insulin; Lipids; Materials science; Metabolic disorders; Microbiota; Nanoparticles; Pathogenesis; Stimuli; Stomach; Weight

Gut dysbiosis has been found to be involved in the pathogenesis of energy metabolic disorders and might be a new strategy for these ailments. Berberine (BBR), a botanical medicine, shows therapeutic efficacy in patients with metabolic diseases. Numerous reports have shown BBR's modulating effec...