Preparation of Liquid Crystalline Molecularly Imprinted Polymer Coated Metal Organic Framework for Capecitabine Delivery

• Published in: Particle & particle systems characterization Vol. 36; no. 1
• Main Authors: Zhang, Li‐Ping, Mo, Chun‐E, Huang, Yan‐Ping, Liu, Zhao‐Sheng
• Format: Journal Article
• Language: English
• Published: Weinheim Wiley Subscription Services, Inc 01.01.2019
• Subjects: Aqueous solutions; Bioavailability; capecitabine; Controlled release; Crystal structure; Crystallinity; drug delivery; Drug delivery systems; Electron microscopes; Fourier transforms; Gravimetric analysis; HKUST‐1; Image transmission; In vivo methods and tests; Infrared analysis; Infrared imagery; liquid crystal monomer; Liquid crystals; Metal-organic frameworks; molecularly imprinted polymer; Monomers; Pharmacology; Polymer coatings; Polymers; Scanning electron microscopy; Thermal stability; X-ray diffraction

A novel molecularly imprinted polymer (MIP) coated metal organic framework (MOF) containing a liquid crystalline (LC) monomer is successfully synthesized for use in drug delivery systems. In this study, [Cu3(BTC)2(H2O)3] n (HKUST‐1) is chosen as the MOF support owing to its large pore volume, good d...