Inhibitory effects of Raphanus sativus root extracts on MUC5AC gene expression in human airway epithelial cells

• Published in: NPJ science of food Vol. 9; no. 1; pp. 181 - 13
• Main Authors: Lu, Jia-Yin, Kuo, Ping-Chung, Li, Yue-Chiun, Chen, Wen-Yin, Hsu, Wei-Li, Tsai, Ching-Hsiu
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 21.08.2025; Nature Publishing Group; Nature Portfolio
• Subjects: 631/92/613; 692/699; 706/1143; Acetic acid; Asthma; Bioactive compounds; Bronchitis; Butyric acid; Cell growth; Chemistry; Chemistry and Materials Science; Chemistry/Food Science; Chronic obstructive pulmonary disease; Colds; Epithelial cells; Epithelium; Ethyl acetate; Food Microbiology; Food Science; Furfural; Gene expression; Glycoproteins; Homeostasis; Mucus; Nutrition; Phorbol 12-myristate 13-acetate; Physiology; Propionic acid; Radishes; Raphanus sativus; Respiratory diseases; Respiratory tract; Variance analysis

The root of Raphanus sativus (radish) is recognized for its bioactive compounds with anti-inflammatory, anti-tumor, and muscle spasm-inhibiting properties. This study explores the effects of different radish extracts on the overexpression of the MUC5AC gene, induced by phorbol 12-myristate 13-acetat...