A thorough clinical study pipeline to discover and validate biomarkers in kidney transplantation: The European BIOMARGIN program

• Published in: Journal of pharmaceutical and biomedical analysis Vol. 263; p. 116911
• Main Authors: Marquet, Pierre, Humeau, Antoine, Anglicheau, Dany, Naesens, Maarten, Gwinner, Wilfried, Thevenot, Etienne A., Labriffe, Marc, Essig, Marie
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 15.09.2025
• Subjects: Biomarkers; Biomarkers - analysis; Biomarkers - blood; Biomarkers - metabolism; Biopsy - methods; Case-Control Studies; Clinical study; Cross-Sectional Studies; Europe; Graft rejection; Graft Rejection - diagnosis; Graft Rejection - metabolism; Humans; Kidney transplantation; Kidney Transplantation - adverse effects; Kidney Transplantation - methods; Longitudinal Studies; Omics; Europe; Biomarkers; Omics; Kidney transplantation; Graft rejection; Clinical study

The European research program BIOMARGIN (Biomarkers of Renal Graft Injuries) seeks to identify and validate non-invasive biomarkers of graft lesions in kidney transplant patients. Graft biopsies represent the gold standard to identify graft lesions, but they are invasive, and their interpretation is...