Dose Emission Characteristics of Placebo PulmoSphere ® Particles Are Unaffected by a Subject's Inhalation Maneuver

• Published in: Journal of aerosol medicine Vol. 26; no. 1; pp. 56 - 68
• Main Authors: Weers, Jeffry, Ung, Keith, Le, John, Rao, Nagaraja, Ament, Brian, Axford, George, Maltz, David, Chan, Leo
• Format: Journal Article
• Language: English
• Published: New Rochelle, NY Mary Ann Liebert 01.02.2013; Mary Ann Liebert, Inc
• Subjects: Administration, Inhalation; Adolescent; Adult; Aerosols; Aged; Asthma - drug therapy; Asthma - metabolism; Biological and medical sciences; Child; Drug Delivery Systems; Dry Powder Inhalers; Female; General pharmacology; Humans; Male; Medical sciences; Medication Adherence; Medication Errors - prevention & control; Middle Aged; Pharmaceutical technology. Pharmaceutical industry; Pharmacology. Drug treatments; Photometry - methods; Porosity; Powders; Pulmonary Disease, Chronic Obstructive - drug therapy; Pulmonary Disease, Chronic Obstructive - metabolism; Tissue Distribution; Young Adult; Delivery system; Particle; Pharmaceutical technology; flow-rate independence; Placebo; Inhaler; Simoon Inhaler; breathing profiles; PulmoSphere; Inhalation; dose inhalation errors
• ISSN: 1941-2711; 1941-2703; 1941-2703
• DOI: 10.1089/jamp.2012.0973

Good compliance to the prescribed dosing regimen and inhaler instructions for use are critical for asthma/chronic obstructive pulmonary disease (COPD) patients to achieve good control of their disease. We investigated the extent to which a system comprising porous particles delivered with a passive...