Boron-Containing heterocycles as promising pharmacological agents

• Published in: Bioorganic & medicinal chemistry Vol. 63; p. 116748
• Main Authors: Das, Bhaskar C., Adil Shareef, Mohammed, Das, Sasmita, Nandwana, Nitesh K., Das, Yogarupa, Saito, Mariko, Weiss, Louis M.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.06.2022
• Subjects: Azaborines; Benzoxaboroles; Boron - chemistry; Boron - pharmacology; Boron containing Drugs; Boron Containing Heterocycles; Bortezomib; Chemistry, Pharmaceutical; Diazaborines; Oxadiazaboroles; Oxazaborolidines; Oxazoborolidine-ones; Pharmacological agents; Benzoxaboroles; Diazaborines; Boron Containing Heterocycles; Oxazoborolidine-ones; Boron containing Drugs; Pharmacological agents; Oxadiazaboroles; Oxazaborolidines; Azaborines

[Display omitted] The incorporation of the “magic” boron atom has been established as an important new strategy in the field of medicinal chemistry as boron compounds have been shown to form various bonds with their biological targets. Currently, a number of boron-based drugs (e.g. bortezomib, crisa...