Metabolomics in chronic kidney disease

• Published in: Clinica chimica acta Vol. 422; pp. 59 - 69
• Main Author: Zhao, Ying-Yong
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 25.06.2013
• Subjects: Animals; Chronic kidney disease; Humans; Mechanism; Metabolic profiling; Metabolome; Metabolomics; Metabonomics; Renal Insufficiency, Chronic - diagnosis; Renal Insufficiency, Chronic - metabolism; Systems biology; Metabolic profiling; Metabolomics; Chronic kidney disease; Systems biology; Metabonomics; Mechanism

Chronic kidney disease (CKD) represents a major challenge to public healthcare. Traditional clinical biomarkers of renal function (blood urea nitrogen and serum creatinine) are not sensitive or specific enough and only increase significantly after the presence of substantial CKD. Therefore, more sen...