Axon reflex-related hyperemia induced by short local heating is reproducible

• Published in: Microvascular research Vol. 84; no. 3; pp. 351 - 355
• Main Authors: Huang, Chung-Shin, Wang, Shwu-Fen, Tsai, Yuan-Feen
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2012
• Subjects: Adult; Axons - physiology; Blood Flow Velocity; Endothelial Cells - cytology; Female; Humans; Hyperemia - metabolism; Laser-Doppler Flowmetry - methods; Male; Models, Biological; Nitric Oxide - metabolism; Reflex; Regional Blood Flow - physiology; Reproducibility of Results; Temperature; Time Factors; Vasodilation - drug effects

The axon reflex (AR) flare is induced by antidromic activation of afferent C-fibers during nociceptive stimulation. This response has been suggested to be modulated by sympathetic activity and basal level of nitric oxide. In previously used protocols of local thermal hyperemia (LTH), AR flare has be...