High wavenumber Raman spectroscopy in the characterization of urinary metabolites of normal subjects, oral premalignant and malignant patients

• Published in: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Vol. 171; pp. 52 - 59
• Main Authors: Brindha, Elumalai, Rajasekaran, Ramu, Aruna, Prakasarao, Koteeswaran, Dornadula, Ganesan, Singaravelu
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 15.01.2017
• Subjects: Adult; Aged; Discriminant Analysis; Female; Flavins; High wavenumber Raman spectroscopy; Humans; Male; Metabolome; Middle Aged; Mouth Neoplasms - metabolism; Mouth Neoplasms - urine; Oral premalignant; PC-LDA; Phenylalanine; Precancerous Conditions - metabolism; Precancerous Conditions - urine; Reference Standards; Spectrum Analysis, Raman; Tryptophan; Urine; Young Adult; High wavenumber Raman spectroscopy; Urine; Phenylalanine; PC-LDA; Tryptophan; Flavins; Oral premalignant

Urine has emerged as one of the diagnostically potential bio fluids, as it has many metabolites. As the concentration and the physiochemical properties of the urinary metabolites may vary under pathological transformation, Raman spectroscopic characterization of urine has been exploited as a signifi...