UPAR targeted molecular imaging of cancers with small molecule-based probes

• Published in: Bioorganic & medicinal chemistry Vol. 25; no. 20; pp. 5179 - 5184
• Main Authors: Ding, Feng, Chen, Seng, Zhang, Wanshu, Tu, Yufeng, Sun, Yao
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 15.10.2017
• Subjects: AE105; Animals; Fluorescent Dyes - chemistry; Humans; Molecular Imaging; Molecular Probes - chemistry; Multimodal imaging; Neoplasms - diagnostic imaging; NIR-II; Receptors, Urokinase Plasminogen Activator - analysis; Small Molecule Libraries - chemistry; Small molecule-based probes; UPAR; Molecular imaging; Small molecule-based probes; Multimodal imaging; NIR-II; UPAR; AE105
• ISSN: 0968-0896; 1464-3391; 1464-3391
• DOI: 10.1016/j.bmc.2017.08.034

[Display omitted] Molecular imaging can allow the non-invasive characterization and measurement of biological and biochemical processes at the molecular and cellular levels in living subjects. The imaging of specific molecular targets that are associated with cancers could allow for the earlier diag...