Resveratrol inhibits matrix metalloproteinase-1 and -3 expression by suppressing of p300/NFκB acetylation in TNF-α-treated human dermal fibroblasts - Lu, Yi-En; Chen, Ying-Jung (Chemico-biological interactions, 2021)
Keywords: Acetylation - drug effects; Binding Sites; Cell Survival - drug effects; Dermal fibroblasts; Down-Regulation - drug effects; E1A-Associated p300 Protein - antagonists & inhibitors; E1A-Associated p300 Protein - genetics; E1A-Associated p300 Protein - metabolism; Fibroblasts - cytology; Fibroblasts - drug effects; Fibroblasts - metabolism; Humans; Matrix metalloproteinase; Matrix Metalloproteinase 1 - genetics; Matrix Metalloproteinase 1 - metabolism; Matrix Metalloproteinase 3 - genetics; Matrix Metalloproteinase 3 - metabolism; NF-kappa B - metabolism; Nitriles - pharmacology; p300; Phosphorylation - drug effects; Promoter Regions, Genetic; Resveratrol; Resveratrol - pharmacology; RNA Interference; RNA, Small Interfering - metabolism; Sulfones - pharmacology; Transcription Factor RelA - metabolism; Tumor Necrosis Factor-alpha - pharmacology; Up-Regulation - drug effects; Wound healing; p300; Dermal fibroblasts; Wound healing; Matrix metalloproteinase; Resveratrol