Deep Sternal Wound Infections After Cardiac Surgery: A New Australian Tertiary Centre Experience
Deep sternal wound infections (DSWI) after cardiac surgery impose a significant burden to patient outcomes and health care costs. The objective of this study is to identify risk factors, microbiological characteristics and protective factors for deep sternal wound infections following cardiac surger...
Saved in:
Published in | Heart, lung & circulation Vol. 29; no. 10; pp. 1571 - 1578 |
---|---|
Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Australia
Elsevier B.V
01.10.2020
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Deep sternal wound infections (DSWI) after cardiac surgery impose a significant burden to patient outcomes and health care costs. The objective of this study is to identify risk factors, microbiological characteristics and protective factors for deep sternal wound infections following cardiac surgery in an Australian hospital.
We performed a retrospective study on 1,902 patients who underwent cardiac surgery at Fiona Stanley Hospital, a tertiary hospital in Western Australia from February 2015 to April 2019. Patients were grouped into having either deep sternal wound infections or no wound infections.
Of 1,902 patients, 26 (1.4%) patients had DSWI. On multivariate analysis, male gender was associated with DSWI with an adjusted odds ratio of 7.390 (95% CI 1.189–45.918, p=0.032). Increased body mass index (BMI) had an odds ratio of 1.101 (95% 1.03–1.18, p=0.008). Increased length of stay (LOS) had an odds ratio of 1.05 (95% CI 1.02–1.08, p=0.002). Left main disease had an odds ratio of 3.076 (95% CI 1.204–7.86, p=0.019). The presence of hypercholesterolaemia had an odds ratio of 0.043 (95% CI 0.009–0.204, p<0.001). Staphylococcus aureus and Staphylococcus epidermidis were the most common organisms found in deep sternal wound infections (23.1% and 26.9% respectively). Polymicrobial growth occurred in 19.2% of patients. One gram of topical cephazolin was applied in 315 patients. None of these patients developed a deep sternal wound infection (p=0.022).
In a large Australian tertiary centre, male gender, increased BMI, presence of left main coronary artery disease, and increased length of hospital stay are significantly associated with the risk of deep sternal wound infections. Staphylococcus aureus and Staphylococcus epidermidis are common organisms in deep sternal wound infections. Topical antibiotics such as cephazolin are useful in preventing deep sternal wound infections. The presence of hypercholesterolaemia is a protective factor and we hypothesise that this is due to long-term statin use. |
---|---|
AbstractList | Deep sternal wound infections (DSWI) after cardiac surgery impose a significant burden to patient outcomes and health care costs. The objective of this study is to identify risk factors, microbiological characteristics and protective factors for deep sternal wound infections following cardiac surgery in an Australian hospital.
We performed a retrospective study on 1,902 patients who underwent cardiac surgery at Fiona Stanley Hospital, a tertiary hospital in Western Australia from February 2015 to April 2019. Patients were grouped into having either deep sternal wound infections or no wound infections.
Of 1,902 patients, 26 (1.4%) patients had DSWI. On multivariate analysis, male gender was associated with DSWI with an adjusted odds ratio of 7.390 (95% CI 1.189-45.918, p=0.032). Increased body mass index (BMI) had an odds ratio of 1.101 (95% 1.03-1.18, p=0.008). Increased length of stay (LOS) had an odds ratio of 1.05 (95% CI 1.02-1.08, p=0.002). Left main disease had an odds ratio of 3.076 (95% CI 1.204-7.86, p=0.019). The presence of hypercholesterolaemia had an odds ratio of 0.043 (95% CI 0.009-0.204, p<0.001). Staphylococcus aureus and Staphylococcus epidermidis were the most common organisms found in deep sternal wound infections (23.1% and 26.9% respectively). Polymicrobial growth occurred in 19.2% of patients. One gram of topical cephazolin was applied in 315 patients. None of these patients developed a deep sternal wound infection (p=0.022).
In a large Australian tertiary centre, male gender, increased BMI, presence of left main coronary artery disease, and increased length of hospital stay are significantly associated with the risk of deep sternal wound infections. Staphylococcus aureus and Staphylococcus epidermidis are common organisms in deep sternal wound infections. Topical antibiotics such as cephazolin are useful in preventing deep sternal wound infections. The presence of hypercholesterolaemia is a protective factor and we hypothesise that this is due to long-term statin use. BACKGROUNDDeep sternal wound infections (DSWI) after cardiac surgery impose a significant burden to patient outcomes and health care costs. The objective of this study is to identify risk factors, microbiological characteristics and protective factors for deep sternal wound infections following cardiac surgery in an Australian hospital. METHODSWe performed a retrospective study on 1,902 patients who underwent cardiac surgery at Fiona Stanley Hospital, a tertiary hospital in Western Australia from February 2015 to April 2019. Patients were grouped into having either deep sternal wound infections or no wound infections. RESULTSOf 1,902 patients, 26 (1.4%) patients had DSWI. On multivariate analysis, male gender was associated with DSWI with an adjusted odds ratio of 7.390 (95% CI 1.189-45.918, p=0.032). Increased body mass index (BMI) had an odds ratio of 1.101 (95% 1.03-1.18, p=0.008). Increased length of stay (LOS) had an odds ratio of 1.05 (95% CI 1.02-1.08, p=0.002). Left main disease had an odds ratio of 3.076 (95% CI 1.204-7.86, p=0.019). The presence of hypercholesterolaemia had an odds ratio of 0.043 (95% CI 0.009-0.204, p<0.001). Staphylococcus aureus and Staphylococcus epidermidis were the most common organisms found in deep sternal wound infections (23.1% and 26.9% respectively). Polymicrobial growth occurred in 19.2% of patients. One gram of topical cephazolin was applied in 315 patients. None of these patients developed a deep sternal wound infection (p=0.022). CONCLUSIONIn a large Australian tertiary centre, male gender, increased BMI, presence of left main coronary artery disease, and increased length of hospital stay are significantly associated with the risk of deep sternal wound infections. Staphylococcus aureus and Staphylococcus epidermidis are common organisms in deep sternal wound infections. Topical antibiotics such as cephazolin are useful in preventing deep sternal wound infections. The presence of hypercholesterolaemia is a protective factor and we hypothesise that this is due to long-term statin use. |
Author | Merry, Chris Bibo, Liam Pierre, Madison Ali, Umar Raichel, Lior Larbalestier, Robert Bayfield, Nicholas |
Author_xml | – sequence: 1 givenname: Umar surname: Ali fullname: Ali, Umar email: umarali39@gmail.com – sequence: 2 givenname: Liam surname: Bibo fullname: Bibo, Liam – sequence: 3 givenname: Madison orcidid: 0000-0002-0282-5714 surname: Pierre fullname: Pierre, Madison – sequence: 4 givenname: Nicholas orcidid: 0000-0002-5860-8153 surname: Bayfield fullname: Bayfield, Nicholas – sequence: 5 givenname: Lior surname: Raichel fullname: Raichel, Lior – sequence: 6 givenname: Chris surname: Merry fullname: Merry, Chris – sequence: 7 givenname: Robert surname: Larbalestier fullname: Larbalestier, Robert |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32173262$$D View this record in MEDLINE/PubMed |
BookMark | eNp9kMFOGzEQhq2KqkDoA_SCfOSy27G9WTtwilKgSKg9AOJoHHvcOtp4g71b4O3rENojpxlpvvk18x2SvdhHJOQLg5oBa7-u6t-drTlwqIHXAOIDOWBN01Rczfjeay-q2RTafXKY8wqAyUbMPpF9wZkUvOUH5OEb4obeDJii6eh9P0ZHr6JHO4Q-Zjr3ZUIXJrlgLL0Z0y9ML6d0Tn_gE52PeUimCybSW0xDMOmFLjAOCen58wZTwGjxiHz0psv4-a1OyN3F-e3ie3X98_JqMb-urJiKoZI4RYWtkw7QKuuxUUp5r8ALp-xSGuOUtOg8OGDCurYRsERvlVp6Z1GICTnZ5W5S_zhiHvQ6ZItdZyL2Y9ZcSNmqppHTgrIdalOfc0KvNymsy_Wagd6K1StdxOqtWA1cF7Fl5_gtflyu0f3f-GeyAGc7AMuTfwImne2rABdSsaldH96J_wspuowq |
CitedBy_id | crossref_primary_10_1016_j_procbio_2021_03_025 crossref_primary_10_3390_medicina58101415 crossref_primary_10_1055_s_0041_1731758 crossref_primary_10_30702_ujcvs_23_31_04__OCh053_106113 crossref_primary_10_2147_VHRM_S264415 crossref_primary_10_1093_ofid_ofae157 crossref_primary_10_1186_s12871_022_01675_9 crossref_primary_10_1093_icvts_ivaa292 crossref_primary_10_1093_ofid_ofae225 crossref_primary_10_1111_jocs_16009 crossref_primary_10_1111_iwj_14457 |
Cites_doi | 10.1124/jpet.102.044099 10.1510/icvts.2006.132191 10.1111/imj.13790 10.1016/S0140-6736(06)68041-0 10.1510/icvts.2010.237883 10.1086/668019 10.1097/00005082-200611000-00015 10.1016/S1010-7940(02)00084-2 10.1016/S0735-1097(02)02340-9 10.1055/s-2008-1038386 10.1016/j.cmi.2015.03.025 10.2147/IDR.S130172 10.1016/j.athoracsur.2009.12.013 10.1016/j.ijcard.2012.09.060 10.1093/bja/aep149 10.1016/j.athoracsur.2005.04.010 10.1016/j.jtcvs.2016.01.060 10.1053/j.jvca.2009.02.007 10.1161/01.CIR.0000084539.58092.DE 10.1111/j.1445-2197.2008.04467.x 10.1016/j.ejcts.2006.09.020 10.1185/030079907X210570 10.1590/S0102-76382008000100007 10.1007/s11748-015-0615-y 10.1016/j.athoracsur.2014.02.089 10.1093/icvts/ivs254 10.1080/14017430801919557 |
ContentType | Journal Article |
Copyright | 2020 Crown Copyright © 2020. Published by Elsevier B.V. All rights reserved. |
Copyright_xml | – notice: 2020 – notice: Crown Copyright © 2020. Published by Elsevier B.V. All rights reserved. |
DBID | CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
DOI | 10.1016/j.hlc.2020.02.003 |
DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
DatabaseTitleList | MEDLINE MEDLINE - Academic |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
EISSN | 1444-2892 |
EndPage | 1578 |
ExternalDocumentID | 10_1016_j_hlc_2020_02_003 32173262 S1443950620300664 |
Genre | Journal Article |
GeographicLocations | Western Australia |
GeographicLocations_xml | – name: Western Australia |
GroupedDBID | --- --K --M .1- .FO .~1 0R~ 1B1 1OC 1P~ 1RT 1~. 1~5 4.4 457 4G. 53G 5GY 5VS 7-5 71M 8-1 8P~ AABNK AACTN AAEDT AAEDW AAIAV AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AAWTL AAXUO ABBQC ABDBF ABFNM ABJNI ABLVK ABMAC ABMZM ABXDB ABYKQ ACDAQ ACGFS ACRLP ACXQS ADBBV ADEZE ADMUD AEBSH AEKER AENEX AEVXI AFCTW AFKWA AFRHN AFTJW AFXIZ AFZJQ AGHFR AGUBO AGYEJ AIEXJ AIKHN AITUG AJAOE AJBFU AJOXV AJRQY AJUYK ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ ANZVX ASPBG AVWKF AXJTR AZFZN B0M BFHJK BKOJK BLXMC BNPGV CAG CO8 COF CS3 DU5 EAD EAP EBS EFJIC EFLBG EJD EMK EO8 EO9 EP2 EP3 ESX EX3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-Q GBLVA HVGLF HX~ HZ~ IHE J1W KOM KTM LCYCR M41 MO0 N9A O-L O9- OAUVE OA~ OL0 OVD OZT P-8 P-9 PC. Q38 R2- RIG ROL RPZ SDF SDG SEL SES SEW SPCBC SSH SSZ T5K TEORI WOQ WOW YFH Z5R ~8M ~G- AAXKI ADVLN AFJKZ AKRWK CGR CUY CVF ECM EIF NPM AAYXX ACRPL ADNMO CITATION 7X8 |
ID | FETCH-LOGICAL-c353t-7e5e8e6d7d0ec8cfe4888ff80f3d8cb7aad87cedf0d013cd6430befc88bfdce33 |
IEDL.DBID | AIKHN |
ISSN | 1443-9506 |
IngestDate | Wed Dec 04 03:43:45 EST 2024 Fri Dec 06 01:58:47 EST 2024 Sat Sep 28 08:37:30 EDT 2024 Fri Feb 23 02:47:48 EST 2024 |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 10 |
Keywords | Infection Cardiac surgery CABG Sternal wound infection |
Language | English |
License | Crown Copyright © 2020. Published by Elsevier B.V. All rights reserved. |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c353t-7e5e8e6d7d0ec8cfe4888ff80f3d8cb7aad87cedf0d013cd6430befc88bfdce33 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ORCID | 0000-0002-0282-5714 0000-0002-5860-8153 |
PMID | 32173262 |
PQID | 2377684475 |
PQPubID | 23479 |
PageCount | 8 |
ParticipantIDs | proquest_miscellaneous_2377684475 crossref_primary_10_1016_j_hlc_2020_02_003 pubmed_primary_32173262 elsevier_sciencedirect_doi_10_1016_j_hlc_2020_02_003 |
PublicationCentury | 2000 |
PublicationDate | October 2020 2020-Oct 2020-10-00 20201001 |
PublicationDateYYYYMMDD | 2020-10-01 |
PublicationDate_xml | – month: 10 year: 2020 text: October 2020 |
PublicationDecade | 2020 |
PublicationPlace | Australia |
PublicationPlace_xml | – name: Australia |
PublicationTitle | Heart, lung & circulation |
PublicationTitleAlternate | Heart Lung Circ |
PublicationYear | 2020 |
Publisher | Elsevier B.V |
Publisher_xml | – name: Elsevier B.V |
References | Ariyaratnam, Bland, Loubani (bib13) 2010; 11 Sjogren, Nilsson, Gustafsson, Malmsjo, Ingemansson (bib2) 2005; 80 Ma, Li, Li, Wu (bib19) 2015; 43 Sakamoto, Fukuda, Oosaka, Nakata (bib7) 2003; 9 Lazar, Salm, Engelman, Orgill, Gordon (bib27) 2016; 152 Gardlund, Bitkover, Vaage (bib6) 2002; 21 Mehra, Uber, Vivekananthan, Solis, Scott, Park (bib26) 2002; 40 Brookes, McGown, Reilly (bib23) 2009; 103 Filsoufi, Castillo, Rahmanian, Broumand, Silvay, Carpentier (bib9) 2009; 23 Sasaki, Bharwani, Jordan, Joh, Manas, Warren (bib25) 2003; 305 Reddy (bib31) 2016; 8 O'Brien, Saxena, Reid, Tran, Baker, Newcomb (bib16) 2018; 48 Yusuf, Chan, Renz, Trampuz (bib8) 2018; 11 Kayani, Bandeali, Lee, Elayda, Khan, Nambi (bib17) 2013; 168 Node, Fujita, Kitakaze, Hori, Liao (bib22) 2003; 108 Sjogren, Malmsjo, Gustafsson, Ingemansson (bib5) 2006; 30 Elenbaas, Soliman Hamad, Schonberger, Martens, van Zundert, van Straten (bib12) 2010; 89 Steingrimsson, Gottfredsson, Kristinsson, Gudbjartsson (bib14) 2008; 42 Hackam, Mamdani, Li, Redelmeier (bib24) 2006; 367 Steingrimsson, Gottfredsson, Gudmundsdottir, Sjögren, Gudbjartsson (bib30) 2012; 15 Arruda, Braile, Joaquim, Suzuki, Alves (bib28) 2008; 23 Chen, Almeida, Mitnovetski, Goldstein, Lowe, Smith (bib29) 2008; 78 Robinson, Billah, Leder, Reid (bib15) 2007; 6 Schimmer, Sommer, Bensch, Elert, Leyh (bib1) 2008; 56 Osawa, Yoshii, Abraham, Okamoto, Hosaka, Fukuda (bib10) 2016; 64 Fitzmaurice, McWilliams, Nolke, Redmond, McGuinness, O'Donnell (bib21) 2014; 98 Keib, Pelham (bib3) 2006; 21 Upton, Smith, Roberts (bib4) 2005; 118 Tleyjeh, Alasmari, Bin Abdulhak, Riaz, Garbati, Erwin (bib20) 2012; 33 Lemaignen, Birgand, Ghodhbane, Alkhoder, Lolom, Belorgey (bib11) 2015; 21 Coleman, Lucek, Hammond, White (bib18) 2007; 23 Fitzmaurice (10.1016/j.hlc.2020.02.003_bib21) 2014; 98 Chen (10.1016/j.hlc.2020.02.003_bib29) 2008; 78 Yusuf (10.1016/j.hlc.2020.02.003_bib8) 2018; 11 Filsoufi (10.1016/j.hlc.2020.02.003_bib9) 2009; 23 Arruda (10.1016/j.hlc.2020.02.003_bib28) 2008; 23 Node (10.1016/j.hlc.2020.02.003_bib22) 2003; 108 Schimmer (10.1016/j.hlc.2020.02.003_bib1) 2008; 56 Lazar (10.1016/j.hlc.2020.02.003_bib27) 2016; 152 Upton (10.1016/j.hlc.2020.02.003_bib4) 2005; 118 Lemaignen (10.1016/j.hlc.2020.02.003_bib11) 2015; 21 Sakamoto (10.1016/j.hlc.2020.02.003_bib7) 2003; 9 O'Brien (10.1016/j.hlc.2020.02.003_bib16) 2018; 48 Sjogren (10.1016/j.hlc.2020.02.003_bib5) 2006; 30 Ariyaratnam (10.1016/j.hlc.2020.02.003_bib13) 2010; 11 Elenbaas (10.1016/j.hlc.2020.02.003_bib12) 2010; 89 Robinson (10.1016/j.hlc.2020.02.003_bib15) 2007; 6 Kayani (10.1016/j.hlc.2020.02.003_bib17) 2013; 168 Hackam (10.1016/j.hlc.2020.02.003_bib24) 2006; 367 Steingrimsson (10.1016/j.hlc.2020.02.003_bib30) 2012; 15 Reddy (10.1016/j.hlc.2020.02.003_bib31) 2016; 8 Brookes (10.1016/j.hlc.2020.02.003_bib23) 2009; 103 Mehra (10.1016/j.hlc.2020.02.003_bib26) 2002; 40 Gardlund (10.1016/j.hlc.2020.02.003_bib6) 2002; 21 Sjogren (10.1016/j.hlc.2020.02.003_bib2) 2005; 80 Tleyjeh (10.1016/j.hlc.2020.02.003_bib20) 2012; 33 Keib (10.1016/j.hlc.2020.02.003_bib3) 2006; 21 Sasaki (10.1016/j.hlc.2020.02.003_bib25) 2003; 305 Steingrimsson (10.1016/j.hlc.2020.02.003_bib14) 2008; 42 Ma (10.1016/j.hlc.2020.02.003_bib19) 2015; 43 Osawa (10.1016/j.hlc.2020.02.003_bib10) 2016; 64 Coleman (10.1016/j.hlc.2020.02.003_bib18) 2007; 23 |
References_xml | – volume: 168 start-page: 117 year: 2013 end-page: 120 ident: bib17 article-title: Association between statins and infections after coronary artery bypass grafting publication-title: Int J Cardiol contributor: fullname: Nambi – volume: 21 start-page: 674.e11 year: 2015 end-page: 674.e18 ident: bib11 article-title: Sternal wound infection after cardiac surgery: incidence and risk factors according to clinical presentation publication-title: Clin Microbiol Infect contributor: fullname: Belorgey – volume: 21 start-page: 493 year: 2006 end-page: 499 ident: bib3 article-title: Mediastinitis following coronary artery bypass graft surgery: pathogenesis, clinical presentation, risks, and management publication-title: J Cardiovasc Nurs contributor: fullname: Pelham – volume: 56 start-page: 200 year: 2008 end-page: 204 ident: bib1 article-title: Management of poststernotomy mediastinitis: experience and results of different therapy modalities publication-title: Thorac Cardiovasc Surg contributor: fullname: Leyh – volume: 21 start-page: 825 year: 2002 end-page: 830 ident: bib6 article-title: Postoperative mediastinitis in cardiac surgery - microbiology and pathogenesis publication-title: Eur J Cardiothorac Surg contributor: fullname: Vaage – volume: 23 start-page: 488 year: 2009 end-page: 494 ident: bib9 article-title: Epidemiology of deep sternal wound infection in cardiac surgery publication-title: J Cardiothorac Vasc Anesth contributor: fullname: Carpentier – volume: 6 start-page: 167 year: 2007 end-page: 171 ident: bib15 article-title: Factors associated with deep sternal wound infection and haemorrhage following cardiac surgery in Victoria publication-title: Interact Cardiovasc Thorac Surg contributor: fullname: Reid – volume: 89 start-page: 704 year: 2010 end-page: 709 ident: bib12 article-title: Preoperative atrial fibrillation and elevated C-reactive protein levels as predictors of mediastinitis after coronary artery bypass grafting publication-title: Ann Thorac Surg contributor: fullname: van Straten – volume: 103 start-page: 99 year: 2009 end-page: 107 ident: bib23 article-title: Statins for all: the new premed? publication-title: Br J Anaesth contributor: fullname: Reilly – volume: 108 start-page: 839 year: 2003 end-page: 843 ident: bib22 article-title: Short-term statin therapy improves cardiac function and symptoms in patients with idiopathic dilated cardiomyopathy publication-title: Circulation contributor: fullname: Liao – volume: 80 start-page: 1270 year: 2005 end-page: 1275 ident: bib2 article-title: The impact of vacuum-assisted closure on long-term survival after post-sternotomy mediastinitis publication-title: Ann Thorac Surg contributor: fullname: Ingemansson – volume: 118 start-page: U1316 year: 2005 ident: bib4 article-title: Excess cost associated with Staphylococcus aureus poststernotomy mediastinitis publication-title: N Z Med J contributor: fullname: Roberts – volume: 30 start-page: 898 year: 2006 end-page: 905 ident: bib5 article-title: Poststernotomy mediastinitis: a review of conventional surgical treatments, vacuum-assisted closure therapy and presentation of the Lund University Hospital mediastinitis algorithm publication-title: Eur J Cardiothorac Surg contributor: fullname: Ingemansson – volume: 9 start-page: 226 year: 2003 end-page: 232 ident: bib7 article-title: Risk factors and treatment of deep sternal wound infection after cardiac operation publication-title: Ann Thorac Cardiovasc Surg contributor: fullname: Nakata – volume: 305 start-page: 78 year: 2003 end-page: 85 ident: bib25 article-title: The 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor pravastatin reduces disease activity and inflammation in dextran-sulfate induced colitis publication-title: J Pharmacol Exp Ther contributor: fullname: Warren – volume: 23 start-page: 35 year: 2008 end-page: 39 ident: bib28 article-title: The use of the vancomycin paste for sternal hemostasis and mediastinitis prophylaxis publication-title: Rev Bras Cir Cardiovasc contributor: fullname: Alves – volume: 11 start-page: 543 year: 2010 end-page: 546 ident: bib13 article-title: Risk factors and mortality associated with deep sternal wound infections following coronary bypass surgery with or without concomitant procedures in a UK population: a basis for a new risk model? publication-title: Interact Cardiovasc Thorac Surg contributor: fullname: Loubani – volume: 40 start-page: 1609 year: 2002 end-page: 1614 ident: bib26 article-title: Comparative beneficial effects of simvastatin and pravastatin on cardiac allograft rejection and survival publication-title: J Am Coll Cardiol contributor: fullname: Park – volume: 152 start-page: 962 year: 2016 end-page: 972 ident: bib27 article-title: Prevention and management of sternal wound infections publication-title: J Thorac Cardiovasc Surg contributor: fullname: Gordon – volume: 11 start-page: 961 year: 2018 end-page: 968 ident: bib8 article-title: Current perspectives on diagnosis and management of sternal wound infections publication-title: Infect Drug Resist contributor: fullname: Trampuz – volume: 48 start-page: 780 year: 2018 end-page: 785 ident: bib16 article-title: Thirty-day outcomes in Indigenous Australians following coronary artery bypass grafting publication-title: Intern Med J contributor: fullname: Newcomb – volume: 98 start-page: 756 year: 2014 end-page: 764 ident: bib21 article-title: Do statins have a role in the promotion of postoperative wound healing in cardiac surgical patients? publication-title: Ann Thorac Surg contributor: fullname: O'Donnell – volume: 42 start-page: 208 year: 2008 end-page: 213 ident: bib14 article-title: Deep sternal wound infections following open heart surgery in Iceland: a population-based study publication-title: Scand Cardiovasc J contributor: fullname: Gudbjartsson – volume: 43 start-page: 610 year: 2015 end-page: 618 ident: bib19 article-title: Effect of statins on preventing infectious complications after surgery: systematic review and meta-analysis publication-title: J Int Med Res contributor: fullname: Wu – volume: 8 start-page: e506 year: 2016 ident: bib31 article-title: Use of closed incision management with negative pressure therapy for complex cardiac patients publication-title: Cureus contributor: fullname: Reddy – volume: 78 start-page: 333 year: 2008 end-page: 336 ident: bib29 article-title: Managing deep sternal wound infections with vacuum-assisted closure publication-title: ANZ J Surg contributor: fullname: Smith – volume: 15 start-page: 406 year: 2012 end-page: 410 ident: bib30 article-title: Negative-pressure wound therapy for deep sternal wound infections reduces the rate of surgical interventions for early re-infections publication-title: Interact Cardiovasc Thorac Surg contributor: fullname: Gudbjartsson – volume: 64 start-page: 197 year: 2016 end-page: 202 ident: bib10 article-title: Topical spraying of cefazolin and gentamicin reduces deep sternal wound infections after heart surgery: a multicenter, large volume, retrospective study publication-title: Gen Thorac Cardiovasc Surg contributor: fullname: Fukuda – volume: 23 start-page: 1783 year: 2007 end-page: 1790 ident: bib18 article-title: Preoperative statins and infectious complications following cardiac surgery publication-title: Curr Med Res Opin contributor: fullname: White – volume: 367 start-page: 413 year: 2006 end-page: 418 ident: bib24 article-title: Statins and sepsis in patients with cardiovascular disease: a population-based cohort analysis publication-title: Lancet contributor: fullname: Redelmeier – volume: 33 start-page: 1143 year: 2012 end-page: 1151 ident: bib20 article-title: Association between preoperative statin therapy and postoperative infectious complications in patients undergoing cardiac surgery: a systematic review and meta-analysis publication-title: Infect Control Hosp Epidemiol contributor: fullname: Erwin – volume: 305 start-page: 78 issue: 1 year: 2003 ident: 10.1016/j.hlc.2020.02.003_bib25 article-title: The 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor pravastatin reduces disease activity and inflammation in dextran-sulfate induced colitis publication-title: J Pharmacol Exp Ther doi: 10.1124/jpet.102.044099 contributor: fullname: Sasaki – volume: 6 start-page: 167 issue: 2 year: 2007 ident: 10.1016/j.hlc.2020.02.003_bib15 article-title: Factors associated with deep sternal wound infection and haemorrhage following cardiac surgery in Victoria publication-title: Interact Cardiovasc Thorac Surg doi: 10.1510/icvts.2006.132191 contributor: fullname: Robinson – volume: 43 start-page: 610 issue: 5 year: 2015 ident: 10.1016/j.hlc.2020.02.003_bib19 article-title: Effect of statins on preventing infectious complications after surgery: systematic review and meta-analysis publication-title: J Int Med Res contributor: fullname: Ma – volume: 48 start-page: 780 issue: 7 year: 2018 ident: 10.1016/j.hlc.2020.02.003_bib16 article-title: Thirty-day outcomes in Indigenous Australians following coronary artery bypass grafting publication-title: Intern Med J doi: 10.1111/imj.13790 contributor: fullname: O'Brien – volume: 367 start-page: 413 issue: 9508 year: 2006 ident: 10.1016/j.hlc.2020.02.003_bib24 article-title: Statins and sepsis in patients with cardiovascular disease: a population-based cohort analysis publication-title: Lancet doi: 10.1016/S0140-6736(06)68041-0 contributor: fullname: Hackam – volume: 9 start-page: 226 issue: 4 year: 2003 ident: 10.1016/j.hlc.2020.02.003_bib7 article-title: Risk factors and treatment of deep sternal wound infection after cardiac operation publication-title: Ann Thorac Cardiovasc Surg contributor: fullname: Sakamoto – volume: 8 start-page: e506 issue: 2 year: 2016 ident: 10.1016/j.hlc.2020.02.003_bib31 article-title: Use of closed incision management with negative pressure therapy for complex cardiac patients publication-title: Cureus contributor: fullname: Reddy – volume: 11 start-page: 543 issue: 5 year: 2010 ident: 10.1016/j.hlc.2020.02.003_bib13 article-title: Risk factors and mortality associated with deep sternal wound infections following coronary bypass surgery with or without concomitant procedures in a UK population: a basis for a new risk model? publication-title: Interact Cardiovasc Thorac Surg doi: 10.1510/icvts.2010.237883 contributor: fullname: Ariyaratnam – volume: 33 start-page: 1143 issue: 11 year: 2012 ident: 10.1016/j.hlc.2020.02.003_bib20 article-title: Association between preoperative statin therapy and postoperative infectious complications in patients undergoing cardiac surgery: a systematic review and meta-analysis publication-title: Infect Control Hosp Epidemiol doi: 10.1086/668019 contributor: fullname: Tleyjeh – volume: 21 start-page: 493 issue: 6 year: 2006 ident: 10.1016/j.hlc.2020.02.003_bib3 article-title: Mediastinitis following coronary artery bypass graft surgery: pathogenesis, clinical presentation, risks, and management publication-title: J Cardiovasc Nurs doi: 10.1097/00005082-200611000-00015 contributor: fullname: Keib – volume: 21 start-page: 825 issue: 5 year: 2002 ident: 10.1016/j.hlc.2020.02.003_bib6 article-title: Postoperative mediastinitis in cardiac surgery - microbiology and pathogenesis publication-title: Eur J Cardiothorac Surg doi: 10.1016/S1010-7940(02)00084-2 contributor: fullname: Gardlund – volume: 40 start-page: 1609 issue: 9 year: 2002 ident: 10.1016/j.hlc.2020.02.003_bib26 article-title: Comparative beneficial effects of simvastatin and pravastatin on cardiac allograft rejection and survival publication-title: J Am Coll Cardiol doi: 10.1016/S0735-1097(02)02340-9 contributor: fullname: Mehra – volume: 56 start-page: 200 issue: 4 year: 2008 ident: 10.1016/j.hlc.2020.02.003_bib1 article-title: Management of poststernotomy mediastinitis: experience and results of different therapy modalities publication-title: Thorac Cardiovasc Surg doi: 10.1055/s-2008-1038386 contributor: fullname: Schimmer – volume: 21 start-page: 674.e11 issue: 7 year: 2015 ident: 10.1016/j.hlc.2020.02.003_bib11 article-title: Sternal wound infection after cardiac surgery: incidence and risk factors according to clinical presentation publication-title: Clin Microbiol Infect doi: 10.1016/j.cmi.2015.03.025 contributor: fullname: Lemaignen – volume: 11 start-page: 961 year: 2018 ident: 10.1016/j.hlc.2020.02.003_bib8 article-title: Current perspectives on diagnosis and management of sternal wound infections publication-title: Infect Drug Resist doi: 10.2147/IDR.S130172 contributor: fullname: Yusuf – volume: 89 start-page: 704 issue: 3 year: 2010 ident: 10.1016/j.hlc.2020.02.003_bib12 article-title: Preoperative atrial fibrillation and elevated C-reactive protein levels as predictors of mediastinitis after coronary artery bypass grafting publication-title: Ann Thorac Surg doi: 10.1016/j.athoracsur.2009.12.013 contributor: fullname: Elenbaas – volume: 168 start-page: 117 issue: 1 year: 2013 ident: 10.1016/j.hlc.2020.02.003_bib17 article-title: Association between statins and infections after coronary artery bypass grafting publication-title: Int J Cardiol doi: 10.1016/j.ijcard.2012.09.060 contributor: fullname: Kayani – volume: 103 start-page: 99 issue: 1 year: 2009 ident: 10.1016/j.hlc.2020.02.003_bib23 article-title: Statins for all: the new premed? publication-title: Br J Anaesth doi: 10.1093/bja/aep149 contributor: fullname: Brookes – volume: 80 start-page: 1270 issue: 4 year: 2005 ident: 10.1016/j.hlc.2020.02.003_bib2 article-title: The impact of vacuum-assisted closure on long-term survival after post-sternotomy mediastinitis publication-title: Ann Thorac Surg doi: 10.1016/j.athoracsur.2005.04.010 contributor: fullname: Sjogren – volume: 152 start-page: 962 issue: 4 year: 2016 ident: 10.1016/j.hlc.2020.02.003_bib27 article-title: Prevention and management of sternal wound infections publication-title: J Thorac Cardiovasc Surg doi: 10.1016/j.jtcvs.2016.01.060 contributor: fullname: Lazar – volume: 23 start-page: 488 issue: 4 year: 2009 ident: 10.1016/j.hlc.2020.02.003_bib9 article-title: Epidemiology of deep sternal wound infection in cardiac surgery publication-title: J Cardiothorac Vasc Anesth doi: 10.1053/j.jvca.2009.02.007 contributor: fullname: Filsoufi – volume: 108 start-page: 839 issue: 7 year: 2003 ident: 10.1016/j.hlc.2020.02.003_bib22 article-title: Short-term statin therapy improves cardiac function and symptoms in patients with idiopathic dilated cardiomyopathy publication-title: Circulation doi: 10.1161/01.CIR.0000084539.58092.DE contributor: fullname: Node – volume: 78 start-page: 333 issue: 5 year: 2008 ident: 10.1016/j.hlc.2020.02.003_bib29 article-title: Managing deep sternal wound infections with vacuum-assisted closure publication-title: ANZ J Surg doi: 10.1111/j.1445-2197.2008.04467.x contributor: fullname: Chen – volume: 30 start-page: 898 issue: 6 year: 2006 ident: 10.1016/j.hlc.2020.02.003_bib5 article-title: Poststernotomy mediastinitis: a review of conventional surgical treatments, vacuum-assisted closure therapy and presentation of the Lund University Hospital mediastinitis algorithm publication-title: Eur J Cardiothorac Surg doi: 10.1016/j.ejcts.2006.09.020 contributor: fullname: Sjogren – volume: 118 start-page: U1316 issue: 1210 year: 2005 ident: 10.1016/j.hlc.2020.02.003_bib4 article-title: Excess cost associated with Staphylococcus aureus poststernotomy mediastinitis publication-title: N Z Med J contributor: fullname: Upton – volume: 23 start-page: 1783 issue: 8 year: 2007 ident: 10.1016/j.hlc.2020.02.003_bib18 article-title: Preoperative statins and infectious complications following cardiac surgery publication-title: Curr Med Res Opin doi: 10.1185/030079907X210570 contributor: fullname: Coleman – volume: 23 start-page: 35 issue: 1 year: 2008 ident: 10.1016/j.hlc.2020.02.003_bib28 publication-title: Rev Bras Cir Cardiovasc doi: 10.1590/S0102-76382008000100007 contributor: fullname: Arruda – volume: 64 start-page: 197 issue: 4 year: 2016 ident: 10.1016/j.hlc.2020.02.003_bib10 article-title: Topical spraying of cefazolin and gentamicin reduces deep sternal wound infections after heart surgery: a multicenter, large volume, retrospective study publication-title: Gen Thorac Cardiovasc Surg doi: 10.1007/s11748-015-0615-y contributor: fullname: Osawa – volume: 98 start-page: 756 issue: 2 year: 2014 ident: 10.1016/j.hlc.2020.02.003_bib21 article-title: Do statins have a role in the promotion of postoperative wound healing in cardiac surgical patients? publication-title: Ann Thorac Surg doi: 10.1016/j.athoracsur.2014.02.089 contributor: fullname: Fitzmaurice – volume: 15 start-page: 406 issue: 3 year: 2012 ident: 10.1016/j.hlc.2020.02.003_bib30 article-title: Negative-pressure wound therapy for deep sternal wound infections reduces the rate of surgical interventions for early re-infections publication-title: Interact Cardiovasc Thorac Surg doi: 10.1093/icvts/ivs254 contributor: fullname: Steingrimsson – volume: 42 start-page: 208 issue: 3 year: 2008 ident: 10.1016/j.hlc.2020.02.003_bib14 article-title: Deep sternal wound infections following open heart surgery in Iceland: a population-based study publication-title: Scand Cardiovasc J doi: 10.1080/14017430801919557 contributor: fullname: Steingrimsson |
SSID | ssj0017439 |
Score | 2.323026 |
Snippet | Deep sternal wound infections (DSWI) after cardiac surgery impose a significant burden to patient outcomes and health care costs. The objective of this study... BACKGROUNDDeep sternal wound infections (DSWI) after cardiac surgery impose a significant burden to patient outcomes and health care costs. The objective of... |
SourceID | proquest crossref pubmed elsevier |
SourceType | Aggregation Database Index Database Publisher |
StartPage | 1571 |
SubjectTerms | CABG Cardiac surgery Cardiac Surgical Procedures - adverse effects Female Humans Incidence Infection Male Middle Aged Retrospective Studies Risk Factors Staphylococcal Infections - epidemiology Staphylococcal Infections - etiology Sternal wound infection Surgical Wound Infection - epidemiology Surgical Wound Infection - etiology Western Australia - epidemiology |
Title | Deep Sternal Wound Infections After Cardiac Surgery: A New Australian Tertiary Centre Experience |
URI | https://dx.doi.org/10.1016/j.hlc.2020.02.003 https://www.ncbi.nlm.nih.gov/pubmed/32173262 https://search.proquest.com/docview/2377684475 |
Volume | 29 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV05T8MwFLZ6LCwIxFWOykhMSKFu7DQuW1SoWhBd2opuJvEhilBa9RhY-O08x0krhjIwJoqVp8_P7332O4zQTagVOHJOPSp122OJXXMxiz0WmzYxQOl8ZQuFXwat3pg9TYJJCXWKWhibVpnbfmfTM2udv2nkaDbm02ljCFsB2g5Iywc9BcfJyqgK7sjGaqtR_7k32AQTLOfOioxsoBkGFMHNLM3r_dM2MvSJ69xJd7mnXfQzc0PdA7Sf80ccOREPUUmnR-jtQes5Hrp-zvjV3pSE-3mWVbrEkb0HHHcyXZB46Aqh73GEwcLh7WEHHtkc63jxhbMjX423bZCP0bj7OOr0vPzqBE_SgK68UAea65YKFdGSS6NhnXJjODFUcZmEcax4CBAbooADSgW8hCTaSM4To6Sm9ARV0lmqzxBWzabhsiVjFVrvz-ALPzHAC5lkMpBBDd0WiIm565AhitSxDwHwCguvIL5tQ1pDrMBU_JpmARb8r2HXBf4C1N_GNOJUz9ZL4dPQhhJZCHKcuonZSEFhuwXs1D__308v0J59cpl7l6iyWqz1FTCQVVJH5bvvZj3Xsx9VZdru |
link.rule.ids | 314,780,784,4502,24116,27924,27925,45585,45679 |
linkProvider | Elsevier |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3LT8IwGG8QD3oxGl_4rIknk0lZO1a8EZSAAhcgcqtbHxFjBuFx8OLf7tdug3jAg9ety5pfv37fr_1eCN2GWoEh59SjUtc8Fts9F7HIY5GpEQOUzlc2Ubjbq7aG7HkUjAqokefC2LDKTPenOt1p6-xJOUOzPB2Py304CtBaQKo-yCkYTraFtlkA7BeE-v57FefhGLdLMbJuZhieuzZdkNf7py1j6JO0bifdZJw2kU9nhJr7aC9jj7ieTvAAFXRyiN4etZ7iflrNGb_aPkm4ncVYJXNct13AccNJgsT9NA36Adcx6De8vurAAxthHc2-sLvw1XhdBPkIDZtPg0bLyxoneJIGdOGFOtBcV1WoiJZcGg27lBvDiaGKyziMIsVDANgQBQxQKmAlJNZGch4bJTWlx6iYTBJ9irCqVAyXVRmp0Np-BiP82AArZJLJQAYldJcjJqZpfQyRB459CIBXWHgF8W0R0hJiOabi1yIL0N9_fXaT4y9A-K1HI0r0ZDkXPg2tI5GFMI-TdGFWs6Bw2AJu6p_976fXaKc16HZEp917OUe79k0aw3eBiovZUl8CF1nEV07WfgBPV9vH |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Deep+Sternal+Wound+Infections+After+Cardiac+Surgery%3A+A+New+Australian+Tertiary+Centre+Experience&rft.jtitle=Heart%2C+lung+%26+circulation&rft.au=Ali%2C+Umar&rft.au=Bibo%2C+Liam&rft.au=Pierre%2C+Madison&rft.au=Bayfield%2C+Nicholas&rft.date=2020-10-01&rft.eissn=1444-2892&rft.volume=29&rft.issue=10&rft.spage=1571&rft.epage=1578&rft_id=info:doi/10.1016%2Fj.hlc.2020.02.003&rft.externalDBID=NO_FULL_TEXT |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1443-9506&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1443-9506&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1443-9506&client=summon |