An in vitro comparative study of layered-double hydroxide nanoconjugate in the delivery of small interference and short-hairpin ribonucleic acid

• Published in: Bulletin of materials science Vol. 43; no. 1; p. 10
• Main Authors: Acharya, Rituparna, Chakraborty, Monisha, Chakraborty, Jui
• Format: Journal Article
• Language: English
• Published: Bangalore Indian Academy of Sciences 01.12.2020; Springer Nature B.V
• Subjects: Biocompatibility; Chemistry and Materials Science; Comparative studies; Engineering; Gene expression; Interference; Macromolecules; Materials Science; Nanoparticles; Plasmids; Ratios; Ribonucleic acid; RNA; United States > US; layered-double hydroxide; siRNA; Alzheimer’s disease; RNAi therapy; shRNA

Alzheimer’s disease is a disease which cannot be cured completely. In this aspect ribonucleic acid interference (RNAi) therapy is a prospective therapeutic mechanism which can be used for identifying a future curative procedure. RNAi therapy comprises small interfering RNA (siRNA), short hairpin (sh...